Publikace 2021

Vanek P., Zoundjiekpon V., Slodička P., Tichý T., Tesaříková J., Svebisova H., Kovář R., Kurfurstova D., Janíková M., Woitková V., Procházka M., Falt P., Urban O. Panceratic cancer screening: ready for prime time? Gasroenerologie a Hepatologie October 2021, 75(5): 390-398

Surgical treatment of duodenal adenocarcinoma: ampullary vs. non-ampullary, short- and long-term outcomes. Tesarikova J, Skalicky P, Kurfurstova D, Svebisova H, Urban O, Falt P, Zapletalova J, Klos D, Lovecek M.Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2021 May 11. doi: 10.5507/bp.2021.028. Online ahead of print.PMID: 34012147

Epithelial to mesenchymal transition and microRNA expression are associated with spindle and apocrine cell morphology in triple-negative breast cancer.

Koleckova M, Ehrmann J, Bouchal J, Janikova M, Brisudova A, Srovnal J, Staffova K, Svoboda M, Slaby O, Radova L, Vomackova K, Melichar B, Veverkova L, Kolar Z. Sci Rep. 2021 Mar 4;11(1):5145. doi: 10.1038/s41598-021-84350-2.PMID: 33664322

Gorlin-Goltz syndrome with familial manifestation. Pazdera J, Santava A, Kolar Z.Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2021 Feb 4. doi: 10.5507/bp.2020.063. Online ahead of print.PMID: 33542540

Complex Alterations of Fatty Acid Metabolism and Phospholipidome Uncovered in Isolated Colon Cancer Epithelial Cells. Hofmanová J, Slavík J, Ciganek M, Ovesná P, Tylichová Z, Karasová M, Zapletal O, Straková N, Procházková J, Bouchal J, Kolář Z, Ehrmann J, Levková M, Hušková Z, Skalický P, Kozubík A, Machala M, Vondráček J.Int J Mol Sci. 2021 Jun 22;22(13):6650. doi: 10.3390/ijms22136650.PMID: 34206240 

Secretory IgA N-glycans contribute to the protection against E. coli O55 infection of germ-free piglets. Raskova Kafkova L, Brokesova D, Krupka M, Stehlikova Z, Dvorak J, Coufal S, Fajstova A, Srutkova D, Stepanova K, Hermanova P, Stepankova R, Uberall I, Skarda J, Novak Z, Vannucci L, Tlaskalova-Hogenova H, Jiraskova Zakostelska Z, Sinkora M, Mestecky J, Raska M.Mucosal Immunol. 2021 Mar;14(2):511-522. doi: 10.1038/s41385-020-00345-8. Epub 2020 Sep 24.PMID: 32973324 

 LC3A positive "stone like structures" are differentially associated with survival outcomes and CD68 macrophage infiltration in patients with lung adenocarcinoma and squamous cell carcinoma.

Gachechiladze M, Uberall I, Skanderova D, Matchavariani J, Ibrahim M, Shani I, Smickova P, Kolek V, Cierna L, Klein J, Stahel R, Joerger M, Soltermann A, Skarda J. Lung Cancer. 2021 Jun;156:129-135. doi: 10.1016/j.lungcan.2021.04.008. Epub 2021 Apr 15.PMID: 33962766

Low Plasma Citrate Levels and Specific Transcriptional Signatures Associated with Quiescence of CD34+ Progenitors Predict Azacitidine Therapy Failure in MDS/AML Patients. Koralkova P, Belickova M, Kundrat D, Dostalova Merkerova M, Krejcik Z, Szikszai K, Kaisrlikova M, Vesela J, Vyhlidalova P, Stetka J, Hlavackova A, Suttnar J, Flodr P, Stritesky J, Jonasova A, Cermak J, Divoky V.Cancers (Basel). 2021 Apr 30;13(9):2161. doi: 10.3390/cancers13092161.PMID: 33946220 

The number of lymphocytes increases in the periprosthetic tissues with increasing time of implant service in non-metal-on-metal total joint arthroplasties: A role of metallic particles? Hobza M, Milde D, Slobodova Z, Gallo J.Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2021 Nov;165(4):416-427. doi: 10.5507/bp.2020.019. Epub 2020 May 18.PMID: 32435063

Plectin ensures intestinal epithelial integrity and protects colon against colitis.

Krausova A, Buresova P, Sarnova L, Oyman-Eyrilmez G, Skarda J, Wohl P, Bajer L, Sticova E, Bartonova L, Pacha J, Koubkova G, Prochazka J, Spörrer M, Dürrbeck C, Stehlikova Z, Vit M, Ziolkowska N, Sedlacek R, Jirak D, Kverka M, Wiche G, Fabry B, Korinek V, Gregor M.Mucosal Immunol. 2021 May;14(3):691-702. doi: 10.1038/s41385-021-00380-z. Epub 2021 Mar 5.PMID: 33674761 

Skp2 and Slug Are Coexpressed in Aggressive Prostate Cancer and Inhibited by Neddylation Blockade. Mickova A, Kharaishvili G, Kurfurstova D, Gachechiladze M, Kral M, Vacek O, Pokryvkova B, Mistrik M, Soucek K, Bouchal J.Int J Mol Sci. 2021 Mar 11;22(6):2844. doi: 10.3390/ijms22062844.PMID: 33799604

Coexistent neck enteric cyst and intraspinal neurenteric cyst: Embryopathogenetic implications.  Starek I, Herman J, Salzman R, Belakova P, Skanderova D.Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2021 Sep;165(3):332-335. doi: 10.5507/bp.2020.030. Epub 2020 Jul 15.PMID: 32686772 

Possible Therapeutic Potential of Disulfiram for Multiple Myeloma. Weiser Drozdkova D, Smesny Trtkova K. Curr Oncol. 2021 Jun 3;28(3):2087-2096. doi: 10.3390/curroncol28030193.

HELLP syndrom a HELLP-like syndrom u těhotných s covid-19 – kazuistiky. Čivrná J. ;  Skanderová D. ;  Ehrmann J. ;  Pilka R.. Ceska Gynekol 2021; 86(4): 236-241

Publikace 2020

Peroxisome proliferator-activated receptor ɑ (PPARɑ)-cytochrome P450 epoxygenases-soluble epoxide hydrolase axis in ER + PR + HER2- breast cancer. Tauber Z, Koleckova M, Cizkova K. Med Mol Morphol. 2020 Sep;53(3):141-148. doi: 10.1007/s00795-019-00240-7. Epub 2019 Dec 10.PMID: 31823010

The number of lymphocytes increases in the periprosthetic tissues with increasing time of implant service in non-metal-on-metal total joint arthroplasties: A role of metallic byproducts? Hobza M, Milde D, Slobodova Z, Gallo J. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2020 May 18. doi: 10.5507/bp.2020.019. Online ahead of print.PMID: 32435063

Pseudoactinomycotic radiate granules in the maxillary sinus. A case report. Starek I, Horacek J, Salzman R. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2020 Sep;164(3):320-323. doi: 10.5507/bp.2019.012. Epub 2019 Apr 17.PMID: 31012440 

Prognostic and predictive markers for perineural and bone invasion of oral squamous cell carcinoma. Michalek J, Brychtova S, Pink R, Dvorak Z. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2019 Dec;163(4):302-308. doi: 10.5507/bp.2019.032. Epub 2019 Aug 21.PMID: 31435075

Tumor infiltrating lymphocytes in malignant melanoma - allies or foes? Zidlik V, Bezdekova M, Brychtova S. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2020 Mar;164(1):43-48. doi: 10.5507/bp.2019.048. Epub 2019 Oct 24.PMID: 31649385 

Association between negative preoperative axillary node staging and surgical sentinel node biopsy in patients with newly diagnosed breast cancer: A retrospective analysis. Veverkova L, Melichar B, Zlamalova N, Vomackova K, Koleckova M, Thomas RP. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2020 Feb 25. doi: 10.5507/bp.2020.005. Online ahead of print.PMID: 32116311

Autophagy role(s) in response to oncogenes and DNA replication stress. Vanzo R, Bartkova J, Merchut-Maya JM, Hall A, Bouchal J, Dyrskjøt L, Frankel LB, Gorgoulis V, Maya-Mendoza A, Jäättelä M, Bartek J. Cell Death Differ. 2020 Mar;27(3):1134-1153. doi: 10.1038/s41418-019-0403-9. Epub 2019 Aug 14.PMID: 31409894 

Predictive and Prognostic Value of DNA Damage Response Associated Kinases in Solid Tumors. Gachechiladze M, Skarda J, Bouchalova K, Soltermann A, Joerger M. Front Oncol. 2020 Nov 3;10:581217. doi: 10.3389/fonc.2020.581217. eCollection 2020.PMID: 33224881

Malignant Granular Cell Tumor of the Esophagus: A Case Report. Stašek M, Aujeský R, Škarda J, Švébišová H, Vrba R, Szkorupa M, Neoral C. Ann Thorac Cardiovasc Surg. 2020 Oct 2. doi: 10.5761/atcs.cr.20-00117. Online ahead of print.PMID: 33012751 

Prognostic value of tumor-infiltrating lymphocytes (TILs) and their association with PD-L1 expression and DNA repair protein RAD51 in patients with resected non-small cell lung carcinoma. Gachechiladze M, Škarda J, Skanderová D, Überall I, Kolek V, Smičkova P, Vojta P, Vbrková J, Hajdúch M, Shani I, Kolář Z, Stahel R, Weder W, Rulle U, Soltermann A, Joerger M. Lung Cancer. 2020 Sep;147:30-38. doi: 10.1016/j.lungcan.2020.06.025. Epub 2020 Jun 23.PMID: 32653671

Gene rearrangement detection by next-generation sequencing in patients with non-small cell lung carcinoma. Brisudova A, Skarda J. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2020 Jun;164(2):127-132. doi: 10.5507/bp.2020.015. Epub 2020 Apr 6.PMID: 32284620

DKN1A Gene Expression in Two Multiple Myeloma Cell Lines With Different P53 Functionality. Drozdkova DH, Gursky J, Minarik J, Überall I, Kolar Z, Trtkova KS. Anticancer Res. 2020 Sep;40(9):4979-4987. doi: 10.21873/anticanres.14501.PMID: 32878786

Molecular mechanisms of plant steroids and study of their interaction with nuclear receptors in prostate cancer cells.Huskova Z, Steigerova J, Oklestkova J, Rarova L, Kolar Z, Strnad M. Food Chem Toxicol. 2020 Mar;137:111164. doi: 10.1016/j.fct.2020.111164. Epub 2020 Jan 27.PMID: 32001316

The Percentage of Free PSA and Urinary Markers Distinguish Prostate Cancer from Benign Hyperplasia and Contribute to a More Accurate Indication for Prostate Biopsy. Huskova Z, Knillova J, Kolar Z, Vrbkova J, Kral M, Bouchal J. Biomedicines. 2020 Jun 25;8(6):173. doi: 10.3390/biomedicines8060173.PMID: 32630458 

Phospholipid profiling enables to discriminate tumor- and non-tumor-derived human colon epithelial cells: Phospholipidome similarities and differences in colon cancer cell lines and in patient-derived cell samples. Hofmanová J, Slavík J, Ovesná P, Tylichová Z, Dušek L, Straková N, Vaculová AH, Ciganek M, Kala Z, Jíra M, Penka I, Kyclová J, Kolář Z, Kozubík A, Machala M, Vondráček J. PLoS One. 2020 Jan 30;15(1):e0228010. doi: 10.1371/journal.pone.0228010. eCollection 2020.PMID: 31999740

Specific alterations of sphingolipid metabolism identified in EpCAM-positive cells isolated from human colon tumors. Procházková J, Slavík J, Bouchal J, Levková M, Hušková Z, Ehrmann J, Ovesná P, Kolář Z, Skalický P, Straková N, Zapletal O, Kozubík A, Hofmanová J, Vondráček J, Machala M. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Sep;1865(9):158742. doi: 10.1016/j.bbalip.2020.158742. Epub 2020 May 21.PMID: 32447053 

Nephrotoxicity of calcineurin inhibitors as a risk factor for BK polyomavirus replication after kidney transplantation. Krejčí K, Tichý T, Bednaříková J, Bartková M, Žamboch K, Orság J, Zadražil J. J Med Virol. 2020 Sep 17. doi: 10.1002/jmv.26520. Online ahead of print.PMID: 32940913

Acute onset of autoimmune hepatitis in children and adolescents. Smolka V, Tkachyk O, Ehrmann J, Karaskova E, Zapalka M, Volejnikova J. Hepatobiliary Pancreat Dis Int. 2020 Feb;19(1):17-21. doi: 10.1016/j.hbpd.2019.08.004. Epub 2019 Aug 24.PMID: 31474443

Nemoc z kočičího škrábnutí s méně obvyklou manifestací a průběhem. Hanulik V., Kybicova K., Brychtova S., Palla V., Stenbersky J., Tichy M. Dermatol. praxi 2020; 14(3): 152-154 | DOI: 10.36290/der.2020.028


Thymoma - diagnostics options. Konvička P, Marek D, Habermann J, Jevík P, Chudáček J, Čtvrtlík F, Michálek J. Vnitr Lek. 2020 Spring;66(2):53-57. English. PMID: 32942888.Objemný exulcerovaný adenomyoepiteliom prsu. Veverkova L., Šišola I., Lowova L., Jankova J., Koleckova M., Zlamalova N., Vomackova K. Onkologie 2020, 14, 13-16.

Slug-expressing mouse prostate epithelial cells have increased stem cell potential. Kahounová Z, Remšík J, Fedr R, Bouchal J, Mičková A, Slabáková E, Binó L, Hampl A, Souček K. Stem Cell Res. 2020 Jul;46:101844. doi: 10.1016/j.scr.2020.101844. Epub 2020 May 12.PMID: 32590255 

Do not underestimate anterior prostate cancer. Kudlackova S, Kurfurstova D, Kral M, Hruska F, Vidlar A, Student V. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2020 Nov 26. doi: 10.5507/bp.2020.054. Online ahead of print.PMID: 33252117

ZEB1: A Critical Regulator of Cell Plasticity, DNA Damage Response, and Therapy Resistance. Drápela S, Bouchal J, Jolly MK, Culig Z, Souček K. Front Mol Biosci. 2020 Mar 19;7:36. doi: 10.3389/fmolb.2020.00036. eCollection 2020.PMID: 32266287

Toll-Like Receptor 3 in Solid Cancer and Therapy Resistance.
Muresan XM, Bouchal J, Culig Z, Souček K. Cancers (Basel). 2020 Nov 2;12(11):3227. doi: 10.3390/cancers12113227.PMID: 33147700

Do not underestimate anterior prostate cancer. Kudlackova S, Kurfurstova D, Kral M, Hruska F, Vidlar A, Student V.Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2021 Jun;165(2):198-202. doi: 10.5507/bp.2020.054. Epub 2020 Nov 26.PMID: 33252117 

Publikace 2019

Variability in Wall Thickness and Related Structures of Major Dural Sinuses in Posterior Cranial Fossa: A Microscopic Anatomical Study and Clinical Implications. Balik V, Uberall I, Sulla I, Ehrmann J, Kato Y, Sulla IJ, Takizawa K. Oper Neurosurg (Hagerstown). 2019 Jul 1;17(1):88-96. doi: 10.1093/ons/opy287. PMID: 30395343

Tumor autophagy is associated with survival outcomes in patients with resected non-small cell lung cancer. Überall I, Gachechiladze M, Joerger M, Anděl J, Smičková P, Kolek V, Grygárková I, Škarda J. Lung Cancer. 2019 Mar;129:85-91. doi: 10.1016/j.lungcan.2019.01.001. Epub 2019 Jan 8. PMID: 30797498

High Skp2 expression is associated with a mesenchymal phenotype and increased tumorigenic potential of prostate cancer cells. Šimečková Š, Kahounová Z, Fedr R, Remšík J, Slabáková E, Suchánková T, Procházková J, Bouchal J, Kharaishvili G, Král M, Beneš P, Souček K. Sci Rep. 2019 Apr 5;9(1):5695. doi: 10.1038/s41598-019-42131-y. PMID: 30952903

Generation of human iPSCs from fetal prostate fibroblasts HPrF. Kahounová Z, Slabáková E, Binó L, Remšík J, Fedr R, Bouchal J, Vrtěl R, Jurečková L, Porokh V, Páralová D, Hampl A, Souček K. Stem Cell Res. 2019 Mar;35:101405. doi: 10.1016/j.scr.2019.101405. Epub 2019 Feb 7. PMID: 30776675

Targeting genotoxic and proteotoxic stress-response pathways in human prostate cancer by clinically available PARP inhibitors, vorinostat and disulfiram. Majera D, Skrott Z, Bouchal J, Bartkova J, Simkova D, Gachechiladze M, Steigerova J, Kurfurstova D, Gursky J, Korinkova G, Cwiertka K, Hodny Z, Mistrik M, Bartek J. Prostate. 2019 Mar;79(4):352-362. doi: 10.1002/pros.23741. Epub 2018 Nov 29. PMID: 30499118

Tumor-Infiltrating Lymphocytes/Plasmocytes in Chemotherapeutically Non-Influenced Triple-Negative Breast Cancers - Correlation with Morphological and Clinico-Pathological Parameters. Kolečková M, Kolář Z, Ehrmann J, Kořínková G, Zlámalová N, Melichar B, Trojanec R. Klin Onkol. 2019 Fall;32(5):380-387. doi: 10.14735/amko2019380. PMID: 31610672

Metastatic Clear Cell Renal Carcinoma Without Evidence of a Primary Renal Tumour Mimicking Advanced Stage of Malignant Lung Tumour. Kolečková M, Tichý T, Melichar B, Veverková L, Hes O, Kolek V, Kolář Z. Klin Onkol. 2019 Spring;32(Supplementum1):154-156. PMID: 31064187

Genetic analysis of subsequent second primary malignant neoplasms in long-term pancreatic cancer survivors suggests new potential hereditary genetic alterations. Lovecek M, Janatova M, Skalicky P, Zemanek T, Havlik R, Ehrmann J, Strouhal O, Zemankova P, Lhotova K, Borecka M, Soukupova J, Svebisova H, Soucek P, Hlavac V, Kleibl Z, Neoral C, Melichar B, Mohelnikova-Duchonova B. Cancer Manag Res. 2019 Jan 10;11:599-609. doi: 10.2147/CMAR.S185352. eCollection 2019. PMID: 30666157

Atypical parkinsonism of progressive supranuclear palsy-parkinsonism (PSP-P) phenotype with rare variants in FBXO7 and VPS35 genes associated with Lewy body pathology. Menšíková K, Tučková L, Kolařiková K, Bartoníková T, Vodička R, Ehrmann J, Vrtěl R, Procházka M, Kaňovský P, Kovacs GG. Acta Neuropathol. 2019 Jan;137(1):171-173. doi: 10.1007/s00401-018-1923-y. Epub 2018 Oct 29. No abstract available.  PMID: 30374525

Sphingosine kinase-1 predicts overall survival outcomes in non-small cell lung cancer patients treated with carboplatin and navelbine. Gachechiladze M, Tichý T, Kolek V, Grygárková I, Klein J, Mgebrishvili G, Kharaishvili G, Janíková M, Smičková P, Cierna L, Pitson S, Maddelein ML, Cuvillier O, Škarda J. Oncol Lett. 2019 Aug;18(2):1259-1266. doi: 10.3892/ol.2019.10447. Epub 2019 Jun 7. PMID: 31423186

Influence of slice thickness on result of CT histogram analysis in indeterminate adrenal masses. Tüdös Z, Kučera P, Szász P, Hartmann I, Langová K, Škarda J, Čtvrtlík F. Abdom Radiol (NY). 2019 Apr;44(4):1461-1469. doi: 10.1007/s00261-018-1835-2. PMID: 30460531

Cochlear Implantation. Skřivan J, Bouček J, Tichý T. Cas Lek Cesk. 2019 Winter;158(6):228-230. PMID: 31931580

Inflammation time-axis in aseptic loosening of total knee arthroplasty: A preliminary study. Dyskova T, Kriegova E, Slobodova Z, Zehnalova S, Kudelka M, Schneiderova P, Fillerova R, Gallo J. PLoS One. 2019 Aug 30;14(8):e0221056. doi: 10.1371/journal.pone.0221056. eCollection 2019. PMID: 31469844

Addiction to DUSP1 protects JAK2V617F-driven polycythemia vera progenitors against inflammatory stress and DNA damage, allowing chronic proliferation. Stetka J, Vyhlidalova P, Lanikova L, Koralkova P, Gursky J, Hlusi A, Flodr P, Hubackova S, Bartek J, Hodny Z, Divoky V. Oncogene. 2019 Jul;38(28):5627-5642. doi: 10.1038/s41388-019-0813-7. Epub 2019 Apr 9. PMID: 30967632

Mass Spectrometry Amyloid Typing Is Reproducible across Multiple Organ Sites. Holub D, Flodrova P, Pika T, Flodr P, Hajduch M, Dzubak P. Biomed Res Int. 2019 Jan 31;2019:3689091. doi: 10.1155/2019/3689091. eCollection 2019. PMID: 30834260

Acute onset of autoimmune hepatitis in children and adolescents. Smolka V, Tkachyk O, Ehrmann J, Karaskova E, Zapalka M, Volejnikova J. Hepatobiliary Pancreat Dis Int. 2020 Feb;19(1):17-21. doi: 10.1016/j.hbpd.2019.08.004. Epub 2019 Aug 24. PMID: 31474443

Generation of human iPSCs from fetal prostate fibroblasts HPrF. Kahounová Z, Slabáková E, Binó L, Remšík J, Fedr R, Bouchal J, Vrtěl R, Jurečková L, Porokh V, Páralová D, Hampl A, Souček K. Stem Cell Res. 2019 Mar;35:101405. doi: 10.1016/j.scr.2019.101405. Epub 2019 Feb 7. PMID: 30776675

Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A. Kahounová Z, Slabáková E, Binó L, Remšík J, Fedr R, Bouchal J, Kurfűrstová D, Vrtěl R, Študent V, Jurečková L, Porokh V, Hampl A, Souček K. Stem Cell Res. 2018 Dec;33:255-259. doi: 10.1016/j.scr.2018.11.006. Epub 2018 Nov 16. PMID: 30481741

High Skp2 expression is associated with a mesenchymal phenotype and increased tumorigenic potential of prostate cancer cells. Šimečková Š, Kahounová Z, Fedr R, Remšík J, Slabáková E, Suchánková T, Procházková J, Bouchal J, Kharaishvili G, Král M, Beneš P, Souček K. Sci Rep. 2019 Apr 5;9(1):5695. doi: 10.1038/s41598-019-42131-y. PMID: 30952903

The Lymphoma-Associated Macrophage to Hodgkin-Reed-Sternberg Cell Ratio Is a Poor Prognostic Factor in Classic Hodgkin Lymphoma Patients. Procházka V, Papajík T, Dýšková T, Dihel M, Brychtová S, Prouzová Z, Kriegová E, Lukášová M, Hanáčková V. Clin Lymphoma Myeloma Leuk. 2019 Oct;19(10):e573-e580. doi: 10.1016/j.clml.2019.07.001. Epub 2019 Jul 5. PMID: 31377208

The changes of angiogenesis and immune regulations in stromal microenvironment of cutaneous melanomas. Židlík V, Uvírová M, Ondruššek R, Dvořáčková J, Brychtová S. Cesk Patol. 2019 Fall;55(3):170-175. PMID: 31726843

Tumor infiltrating lymphocytes in malignant melanoma - allies or foes? Zidlik V, Bezdekova M, Brychtova S. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2020 Mar;164(1):43-48. doi: 10.5507/bp.2019.048. Epub 2019 Oct 24. PMID: 31649385

Prognostic and predictive markers for perineural and bone invasion of oral squamous cell carcinoma. Michalek J, Brychtova S, Pink R, Dvorak Z. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2019 Dec;163(4):302-308. doi: 10.5507/bp.2019.032. Epub 2019 Aug 21. PMID: 31435075

Low-volume metastatic nodal disease in endometrial cancer. Hambálek J, Maděrka M, Kolečková M, Pilka R. Ceska Gynekol. 2019 Winter;84(6):458-462. Review. PMID: 31948256

Peroxisome proliferator-activated receptor ɑ (PPARɑ)-cytochrome P450 epoxygenases-soluble epoxide hydrolase axis in ER + PR + HER2- breast cancer. Tauber Z, Koleckova M, Cizkova K. Med Mol Morphol. 2019 Dec 10. doi: 10.1007/s00795-019-00240-7. [Epub ahead of print] PMID: 31823010

Regulation of S1PR2 by the EBV oncogene LMP1 in aggressive ABC-subtype diffuse large B-cell lymphoma. Vockerodt M, Vrzalikova K, Ibrahim M, Nagy E, Margielewska S, Hollows R, Lupino L, Tooze R, Care M, Simmons W, Schrader A, Perry T, Abdullah M, Foster S, Reynolds G, Dowell A, Rudzki Z, Krappmann D, Kube D, Woodman C, Wei W, Taylor G, Murray PG. J Pathol. 2019 Jun;248(2):142-154. doi: 10.1002/path.5237. Epub 2019 Mar 22. PMID: 30666658

Sphingosine-1-phosphate signalling drives an angiogenic transcriptional programme in diffuse large B cell lymphoma. Lupino L, Perry T, Margielewska S, Hollows R, Ibrahim M, Care M, Allegood J, Tooze R, Sabbadini R, Reynolds G, Bicknell R, Rudzki Z, Lin Hock Y, Zanetto U, Wei W, Simmons W, Spiegel S, Woodman CBJ, Rowe M, Vrzalikova K, Murray PG. Leukemia. 2019 Dec;33(12):2884-2897. doi: 10.1038/s41375-019-0478-9. Epub 2019 May 16. PMID: 31097785

Correction: S1PR1 drives a feedforward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells. Vrzalikova K, Ibrahim M, Vockerodt M, Perry T, Margielewska S, Lupino L, Nagy E, Soilleux E, Liebelt D, Hollows R, Last A, Reynolds G, Abdullah M, Curley H, Care M, Krappmann D, Tooze R, Allegood J, Spiegel S, Wei W, Woodman CBJ, Murray PG. Leukemia. 2019 Aug;33(8):2126. doi: 10.1038/s41375-019-0511-z. PMID: 31239494

Cyst of the right lymphatic duct. Stárek I, Salzman R, Pokorná Z, Skanderová D. Eur Ann Otorhinolaryngol Head Neck Dis. 2020 Mar;137(2):123-125. doi: 10.1016/j.anorl.2019.01.002. Epub 2019 Sep 30. PMID: 31582333

Pseudoactinomycotic radiate granules in the maxillary sinus. A case report. Starek I, Horacek J, Salzman R. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2019 Apr 17. doi: 10.5507/bp.2019.012. [Epub ahead of print] PMID: 31012440

Increased Expression of miR-146a in Valvular Tissue From Patients With Aortic Valve Stenosis. Petrkova J, Borucka J, Kalab M, Klevcova P, Michalek J, Taborsky M, Petrek M. Front Cardiovasc Med. 2019 Jun 26;6:86. doi: 10.3389/fcvm.2019.00086. eCollection 2019. PMID: 31294031

KOLEČKOVÁ, M., TICHÝ, T., MELICHAR, B., VEVERKOVÁ, L., HES, O., KOLEK, V., KOLÁŘ, Z. Metastazující světlobuněčný renální karcinom bez zjevného primárního ložiska v ledvině imitující pokročilé stadium plicní malignity. Klinicka Onkologie, 2019, roč. 32, č. Suppl. 1, s. 154-156. ISSN 0862-495X.

HAMBÁLEK, J., MADĚRKA, M., KOLEČKOVÁ, M., PILKA, R. Nízkoobjemové metastatické postižení lymfatických uzlin u karcinomu endometria. Ceska Gynekologie-Czech Gynaecology, 2019, roč. 84, č. 6, s. 458-462. ISSN 1210-7832.

BIELIKOVÁ, P., PILKA, R., HUML, K., MELICHAR, B., ŠVÉBIŠOVÁ, H., JANKOVÁ, J., PRÁŠIL, V., ZAMBO, I., JANIČEK, P. Monophasic synovial sarcoma of the lower extremity at 20 weeks of pregnancy: a case report and review of the literature. Clinical and Experimental Obstetrics & Gynecology, 2019, roč. XlVI, č. 6, s. 992-998. ISSN 0390-6663.DOI 10.12891/ceog4877.2019

KORPOVÁ, A., STÁREK, I., HOZA, J., ZAPLETALOVÁ, J., MICHÁLEK, J., SALZMAN, R. Hormonálně aktivní ektopický estesioneuroblastom u pediatrické pacientky. Otorinolaryngologie a foniatrie, 2019, roč. 68, č. 4, s. 227-230. ISSN 1210-7867.

MICHÁLEK, J., PINK, R., DVOŘÁK, Z., BRYCHTOVÁ, S., KRÁL, D., TVRDÝ, P., KOLÁŘ, Z. Srovnání histopatologických a klinických prognostických faktorů spinocelulárních karcinomů ústní dutiny. Česká stomatologie, 2019, roč. 119, č. 3, s. 68-79. ISSN 1213-0613.

KOVAŘÍKOVÁ, H., BARANOVÁ, I., LACO, J., MICHÁLEK, J. HPV related deregulation of selected microRNAs in sinonasal squamous cell carcinoma. Klinicka Biochemie a Metabolismus, 2019, roč. 27, č. 3, s. 100-106. ISSN 1210-7921.

KOVAŘÍKOVÁ, H., BARANOVÁ, I., LACO, J., MICHÁLEK, J. Deregulation of Selected MicroRNAs in Sinonasal Squamous Cell Carcinoma: Searching for Potential Prognostic Biomarkers. FOLIA BIOLOGICA, 2019, roč. 65, č. 3, s. 142-151. ISSN 0015-5500.

ŽURKOVÁ, M., TICHÝ, T., LOŠŤÁKOVÁ, V., KOLEK, V., TICHÝ, T., KRIEGOVÁ, E. Sarkoidóza gastrointestinálního traktu a jater. Postgraduální medicína, 2019, roč. 21, č. 2, s. 37-43. ISSN 1212-4184.

MIHÁL, V., MICHL, P., MICHÁLEK, J., MICHÁLKOVÁ, K. Ranula podjazykové žlázy – diagnostická výzva. Pediatrie pro Praxi, 2019, roč. 20, č. 3, s. 175-179. ISSN 1213-0494.

MIHÁL, V., KYSUČAN, J., JANKOVÁ, J., BAKAJ ZBROŽKOVÁ, L., MICHÁLKOVÁ, K. Mezenteriální lipom – vzácná příčina opakovaných bolestí břicha u dítěte. Pediatrie pro Praxi, 2019, roč. 20, č. 2, s. 120-122. ISSN 1213-0494.

PALLA, V., TICHÝ, M., BRYCHTOVÁ, S. Maligní melanom imitující hlubokou mykózu. Dermatologie pro praxi, 2019, roč. 13, č. 4, s. 190-194. ISSN 1802-2960.

KOLEČKOVÁ, M., KOLÁŘ, Z., EHRMANN, J., KOŘÍNKOVÁ, G., ZLÁMALOVÁ, N., MELICHAR, B., TROJANEC, R. Lymfo/plazmocytární infiltrace chemoterapií neovlivněných triple negativních karcinomů prsu - koreláty s morfologickými a klinicko-patologickými parametry. Klinicka Onkologie, 2019, roč. 32, č. 5, s. 380-387. ISSN 0862-495X.DOI 10.14735/amko2019380

BRYCHTOVÁ, S. Patologie kůže. In Patologie. LD, s.r.o. - Prager Publishing, 2019, s. 777-798. ISBN 978-80-270-6457-1

Publikace 2018

Presence of growth/differentiation factor-15 cytokine in human follicular fluid, granulosa cells, and oocytes. Souček K, Malenovská A, Kahounová Z, Remšík J, Holubcová Z, Soukup T, Kurfürstová D, Bouchal J, Suchánková T, Slabáková E, Hampl A. J Assist Reprod Genet. 2018 Aug;35(8):1407-1417. doi: 10.1007/s10815-018-1230-5. Epub 2018 Jun 13. PMID: 29948426

Selective inhibition reveals cyclin-dependent kinase 2 as another kinase that phosphorylates the androgen receptor at serine 81. Jorda R, Bučková Z, Řezníčková E, Bouchal J, Kryštof V. Biochim Biophys Acta Mol Cell Res. 2018 Feb;1865(2):354-363. doi: 10.1016/j.bbamcr.2017.11.011. Epub 2017 Nov 20. PMID: 29157894

Olaparib is effective in combination with, and as maintenance therapy after, first-line endocrine therapy in prostate cancer cells. Feiersinger GE, Trattnig K, Leitner PD, Guggenberger F, Oberhuber A, Peer S, Hermann M, Skvortsova I, Vrbkova J, Bouchal J, Culig Z, Santer FR. Mol Oncol. 2018 Apr;12(4):561-576. doi: 10.1002/1878-0261.12185. Epub 2018 Mar 15. PMID: 29465803

Trop-2 plasticity is controlled by epithelial-to-mesenchymal transition. Remšík J, Binó L, Kahounová Z, Kharaishvili G, Šimecková Š, Fedr R, Kucírková T, Lenárt S, Muresan XM, Slabáková E, Knopfová L, Bouchal J, Král M, Beneš P, Soucek K. Carcinogenesis. 2018 Jul 16. doi: 10.1093/carcin/bgy095. [Epub ahead of print] PMID: 30010814

[Can Analysis of Cellular Lipidome Contribute to Discrimination of Tumour and Non-tumour Colon Cells?] Hofmanová J, Slávik J, Tylichová Z, Ovesná P, Bouchal J, Kolář Z, Ehrmann J, Levková M, Machala M, Vondráček J, Kozubík A. Klin Onkol. 2018 Spring;31(Supplementum1):151-154. Czech.  PMID: 29808691

Beneficial Effect of Heat-induced Antigen Retrieval in Immunocytochemical Detection of Intracellular Antigens in Alcohol-fixed Cell Samples. Cizkova K, Flodrova P, Baranova R, Malohlava J, Lacey M, Tauber Z. Appl Immunohistochem Mol Morphol. 2018 Aug 8. doi: 10.1097/PAI.0000000000000689. [Epub ahead of print] PMID: 30095458

Cardiac amyloidosis: from clinical suspicion to morphological diagnosis. Flodrova P, Flodr P, Pika T, Vymetal J, Holub D, Dzubak P, Hajduch M, Scudla V. Pathology. 2018 Apr;50(3):261-268. doi: 10.1016/j.pathol.2017.10.012. Epub 2018 Feb 12. Review. PMID: 29448998

First report of ibrutinib in IgM-related amyloidosis: few responses, poor tolerability, and short survival. Pika T, Hegenbart U, Flodrova P, Maier B, Kimmich C, Schönland SO. Blood. 2018 Jan 18;131(3):368-371. doi: 10.1182/blood-2017-09-806463. Epub 2017 Nov 27. No abstract available.  PMID: 29180400

MicroRNAs in triple-negative breast cancer. Koleckova M, Janikova M, Kolar Z. Neoplasma. 2018;65(1):1-13. doi: 10.4149/neo_2018_170115N36. PMID: 29322783

Elevated DNA methylation in malignant tumors of the sinonasal tract and its association with patient survival. Chmelarova M, Laco J, Kovarikova H, Baranova I, Dundr P, Nemejcova K, Michalek J, Vosmik M, Palicka V. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2018 Sep;162(3):232-238. doi: 10.5507/bp.2018.012. Epub 2018 Mar 27. PMID: 29581595

Analysis of DNA methylation and microRNA expression in NUT (nuclear protein in testis) midline carcinoma of the sinonasal tract: a clinicopathological, immunohistochemical and molecular genetic study. Laco J, Kovarikova H, Chmelarova M, Vosmikova H, Sieglova K, Bubancova I, Dundr P, Nemejcova K, Michalek J, Celakovsky P, Mottl R, Sirak I, Vosmik M, Marek I, Geryk T, Mejzlik J, Satankova J, Ryska A. Neoplasma. 2018;65(1):113-123. doi: 10.4149/neo_2018_161122N581. PMID: 29322795

The novel brassinosteroid analog BR4848 inhibits angiogenesis in human endothelial cells and induces apoptosis in human cancer cells in vitro. Rárová L, Sedlák D, Oklestkova J, Steigerová J, Liebl J, Zahler S, Bartůněk P, Kolář Z, Kohout L, Kvasnica M, Strnad M. J Steroid Biochem Mol Biol. 2018 Apr;178:263-271. doi: 10.1016/j.jsbmb.2018.01.005. Epub 2018 Jan 4. PMID: 29307714

Real life adjuvant chemotherapy uptake and survival in patients with non-small cell lung cancer after complete resection. Kolek V, Losse S, Kultan J, Jakubec P, Jaromir Z, Sova M, Szkorupa M, Neoral Č, Škarda J, Tichý T, Kolář Z. Curr Med Res Opin. 2018 Sep;34(9):1687-1694. doi: 10.1080/03007995.2018.1490254. Epub 2018 Jul 9. PMID: 29912578

The fibroblast surface markers FAP, anti-fibroblast, and FSP are expressed by cells of epithelial origin and may be altered during epithelial-to-mesenchymal transition. Kahounová Z, Kurfürstová D, Bouchal J, Kharaishvili G, Navrátil J, Remšík J, Šimečková Š, Študent V, Kozubík A, Souček K. Cytometry A. 2018 Jul;93(9):941-951. doi: 10.1002/cyto.a.23101. Epub 2017 Apr 6. PMID: 28383825

Variability in Wall Thickness and Related Structures of Major Dural Sinuses in Posterior Cranial Fossa: A Microscopic Anatomical Study and Clinical Implications. Balik V, Uberall I, Sulla I, Ehrmann J, Kato Y, Sulla IJ, Takizawa K. Oper Neurosurg (Hagerstown). 2018 Nov 2. doi: 10.1093/ons/opy287. [Epub ahead of print] PMID: 30395343

Natural plant hormones cytokinins increase stress resistance and longevity of Caenorhabditis elegans. Kadlecová A, Jirsa T, Novák O, Kammenga J, Strnad M, Voller J. Biogerontology. 2018 Apr;19(2):109-120. doi: 10.1007/s10522-017-9742-4. Epub 2017 Dec 18. PMID: 29255944

Selective inhibition reveals cyclin-dependent kinase 2 as another kinase that phosphorylates the androgen receptor at serine 81. Jorda R, Bučková Z, Řezníčková E, Bouchal J, Kryštof V. Biochim Biophys Acta Mol Cell Res. 2018 Feb;1865(2):354-363. doi: 10.1016/j.bbamcr.2017.11.011. Epub 2017 Nov 20. PMID: 29157894

Generation of human iPSCs from human prostate cancer-associated fibroblasts IBPi002-A. Kahounová Z, Slabáková E, Binó L, Remšík J, Fedr R, Bouchal J, Kurfűrstová D, Vrtěl R, Študent V, Jurečková L, Porokh V, Hampl A, Souček K. Stem Cell Res. 2018 Dec;33:255-259. doi: 10.1016/j.scr.2018.11.006. Epub 2018 Nov 16. PMID: 30481741

Infiltration of Prostate Cancer by CD204+ and CD3+ Cells Correlates with ERG Expression and TMPRSS2-ERG Gene Fusion. Burdova A, Rulisek P, Bouchal J, Král M, Student V, Kolar Z. Klin Onkol. 2018 Fall;31(6):421-428. doi: 10.14735/amko2018421. PMID: 30545222

Targeting genotoxic and proteotoxic stress-response pathways in human prostate cancer by clinically available PARP inhibitors, vorinostat and disulfiram. Majera D, Skrott Z, Bouchal J, Bartkova J, Simkova D, Gachechiladze M, Steigerova J, Kurfurstova D, Gursky J, Korinkova G, Cwiertka K, Hodny Z, Mistrik M, Bartek J. Prostate. 2018 Nov 29. doi: 10.1002/pros.23741. [Epub ahead of print] PMID: 30499118

First report of ibrutinib in IgM-related amyloidosis: few responses, poor tolerability, and short survival. Pika T, Hegenbart U, Flodrova P, Maier B, Kimmich C, Schönland SO. Blood. 2018 Jan 18;131(3):368-371. doi: 10.1182/blood-2017-09-806463. Epub 2017 Nov 27. No abstract available.  PMID: 29180400

Co-Expression of the Epstein-Barr Virus-Encoded Latent Membrane Proteins and the Pathogenesis of Classic Hodgkin Lymphoma. Vrzalikova K, Ibrahim M, Nagy E, Vockerodt M, Perry T, Wei W, Woodman C, Murray P. Cancers (Basel). 2018 Aug 24;10(9). pii: E285. doi: 10.3390/cancers10090285. Review. PMID: 30149502

Contribution of Epstein⁻Barr Virus Latent Proteins to the Pathogenesis of Classical Hodgkin Lymphoma. Vrzalikova K, Sunmonu T, Reynolds G, Murray P. Pathogens. 2018 Jun 27;7(3). pii: E59. doi: 10.3390/pathogens7030059. Review. PMID: 29954084

Žarnayová L, Kolek V, Bouchal J, Ehrmann J: Nemalobuněčný karcinom plic s expresí estrogenových receptorů a pozitivitou ALK. Klinická Onkologie 2018; 31: 457-60.

S1PR1 drives a feedforward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells. Vrzalikova K, Ibrahim M, Vockerodt M, Perry T, Margielewska S, Lupino L, Nagy E, Soilleux E, Liebelt D, Hollows R, Last A, Reynolds G, Abdullah M, Curley H, Care M, Krappmann D, Tooze R, Allegood J, Spiegel S, Wei W, Woodman CBJ, Murray PG. Leukemia. 2018 Jan;32(1):214-223. doi: 10.1038/leu.2017.275. Epub 2017 Sep 7. PMID: 28878352

Current diagnostic imaging of pheochromocytomas and implications for therapeutic strategy. Čtvrtlík F, Koranda P, Schovánek J, Škarda J, Hartmann I, Tüdös Z. Exp Ther Med. 2018 Apr;15(4):3151-3160. doi: 10.3892/etm.2018.5871. Epub 2018 Feb 14. PMID: 29545830

Real life adjuvant chemotherapy uptake and survival in patients with non-small cell lung cancer after complete resection. Kolek V, Losse S, Kultan J, Jakubec P, Jaromir Z, Sova M, Szkorupa M, Neoral Č, Škarda J, Tichý T, Kolář Z. Curr Med Res Opin. 2018 Sep;34(9):1687-1694. doi: 10.1080/03007995.2018.1490254. Epub 2018 Jul 9. PMID: 29912578

Author Correction: BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity. Rasmussen RD, Gajjar MK, Tuckova L, Jensen KE, Maya-Mendoza A, Holst CB, Møllgård K, Rasmussen JS, Brennum J, Bartek J Jr, Syrucek M, Sedlakova E, Andersen KK, Frederiksen MH, Bartek J, Hamerlik P. Nat Commun. 2018 Dec 19;9(1):5396. doi: 10.1038/s41467-018-07892-6. PMID: 30568233

Atypical parkinsonism of progressive supranuclear palsy-parkinsonism (PSP-P) phenotype with rare variants in FBXO7 and VPS35 genes associated with Lewy body pathology. Menšíková K, Tučková L, Kolařiková K, Bartoníková T, Vodička R, Ehrmann J, Vrtěl R, Procházka M, Kaňovský P, Kovacs GG. Acta Neuropathol. 2018 Oct 29. doi: 10.1007/s00401-018-1923-y. [Epub ahead of print] No abstract available.  PMID: 30374525

IDH Mutation Analysis in Glioma Patients by CADMA Compared with SNaPshot Assay and two Immunohistochemical Methods. Urbanovska I, Megova MH, Dwight Z, Kalita O, Uvirova M, Simova J, Tuckova L, Buzrla P, Palecek T, Hajduch M, Dvorackova J, Drabek J. Pathol Oncol Res. 2018 Mar 19. doi: 10.1007/s12253-018-0413-9. [Epub ahead of print] PMID: 29556922

miR-150 downregulation contributes to the high-grade transformation of follicular lymphoma by upregulating FOXP1 levels. Musilova K, Devan J, Cerna K, Seda V, Pavlasova G, Sharma S, Oppelt J, Pytlik R, Prochazka V, Prouzova Z, Trbusek M, Zlamalikova L, Liskova K, Kruzova L, Jarosova M, Mareckova A, Kornauth C, Simonitsch-Klupp I, Schiefer AI, Merkel O, Mocikova H, Burda P, Machova Polakova K, Kren L, Mayer J, Zent CS, Trneny M, Evans AG, Janikova A, Mraz M. Blood. 2018 Nov 29;132(22):2389-2400. doi: 10.1182/blood-2018-06-855502. Epub 2018 Sep 13. PMID: 30213873

Critical evaluation of colon submucosal microdialysis in awake, mobile rats. Cibicek N, Ehrmann J, Proskova J, Vecera R. PLoS One. 2018 Jan 11;13(1):e0191041. doi: 10.1371/journal.pone.0191041. eCollection 2018. PMID: 29324792

A case of accelerated silicosis. Nakládalová M, Štepánek L, Kolek V, Žurková M, Tichý T. Occup Med (Lond). 2018 Sep 13;68(7):482-484. doi: 10.1093/occmed/kqy106. PMID: 30053129

BK virus-induced renal allograft nephropathy. Krejci K, Tichy T, Bednarikova J, Zamboch K, Zadrazil J. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2018 Sep;162(3):165-177. doi: 10.5507/bp.2018.018. Epub 2018 May 16. PMID: 29765170

Variability in Wall Thickness and Related Structures of Major Dural Sinuses in Posterior Cranial Fossa: A Microscopic Anatomical Study and Clinical Implications. Balik V, Uberall I, Sulla I, Ehrmann J, Kato Y, Sulla IJ, Takizawa K. Oper Neurosurg (Hagerstown). 2018 Nov 2. doi: 10.1093/ons/opy287. [Epub ahead of print]. PMID: 30395343

Publikace 2017

S1PR1 drives a feedforward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells. Vrzalikova K, Ibrahim M, Vockerodt M, Perry T, Margielewska S, Lupino L, Nagy E, Soilleux E, Liebelt D, Hollows R, Last A, Reynolds G, Abdullah M, Curley H, Care M, Krappmann D, Tooze R, Allegood J, Spiegel S, Wei W, Woodman CBJ, Murray PG. Leukemia. 2017 Sep 7. doi: 10.1038/leu.2017.275. [Epub ahead of print] PMID: 28878352

Single giant mediastinal rhabdomyoma as a sole manifestation of TSC in foetus. Godava M, Filipova H, Dubrava L, Vrtel R, Michalkova K, Janikova M, Bakaj-Zbrozkova L, Navratil J. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2017 Sep;161(3):326-329. doi: 10.5507/bp.2017.023. Epub 2017 Jun 12. PMID: 28659645

Narůstající dyspnoe a tachypnoe jako hlavní příznak kritické vrozené srdeční vady. Klásková E., Flodrová P., Hecht P., Flodr P., Wiedermann J.: Pediatrie pro praxi (2017) 18(1), 52-55.

Nádorem indukovaná hypofosfatémie s osteomalacií – kazuistika. Lokočová E., Cibiček N., Horák P., Flodrová P., Zadražil J.: Osteologický bulletin (2016) 21 (4), 136-141.

CD38-negative relapse in multiple myeloma after daratumumab-based chemotherapy. Minarik J, Novak M, Flodr P, Balcarkova J, Mlynarcikova M, Krhovska P, Pika T, Pikalova Z, Bacovsky J, Scudla V. Eur J Haematol. 2017 Aug;99(2):186-189. doi: 10.1111/ejh.12902. Epub 2017 Jun 6. PMID: 28470777

Deregulation of selected microRNAs in sinonasal carcinoma: Value of miR-21 as prognostic biomarker in sinonasal squamous cell carcinoma. Kovarikova H, Bubancova I, Laco J, Sieglova K, Vosmikova H, Vosmik M, Dundr P, Nemejcova K, Michalek J, Palicka V, Chmelarova M. Head Neck. 2017 Dec;39(12):2528-2536. doi: 10.1002/hed.24930. Epub 2017 Sep 28. PMID: 28960576

SMARCB1/INI1-deficient sinonasal carcinoma shows methylation of RASSF1 gene: A clinicopathological, immunohistochemical and molecular genetic study of a recently described entity. Laco J, Chmelařová M, Vošmiková H, Sieglová K, Bubancová I, Dundr P, Němejcová K, Michálek J, Čelakovský P, Mottl R, Sirák I, Vošmik M, Ryška A. Pathol Res Pract. 2017 Feb;213(2):133-142. doi: 10.1016/j.prp.2016.10.012. Epub 2016 Oct 25. PMID: 28069272

Clonality testing of lymphoproliferative disorders in a large cohort of primary and consultant biopsies. Svachova M, Tichy M, Flodr P, Steigerova J, Kolar Z, Bouchal J. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2017 Jun;161(2):197-205. doi: 10.5507/bp.2017.006. Epub 2017 Mar 14. PMID: 28323289

Laboratorní aspekty systémové AA amyloidózy. Pika T., Heřmanová Z., Flodrová P.: Klinická biochemie a metabolismus (2017), 256-58.

RAD51 as a potential surrogate marker for DNA repair capacity in solid malignancies. Gachechiladze M, Škarda J, Soltermann A, Joerger M. Int J Cancer. 2017 Oct 1;141(7):1286-1294. doi: 10.1002/ijc.30764. Epub 2017 May 19. Review. PMID: 28477336

Prognostic and predictive value of loss of nuclear RAD51 immunoreactivity in resected non-small cell lung cancer patients. Gachechiladze M, Škarda J, Kolek V, Grygárková I, Langová K, Bouchal J, Kolář Z, Baty F, Stahel R, Weder W, Soltermann A, Joerger M. Lung Cancer. 2017 Mar;105:31-38. doi: 10.1016/j.lungcan.2017.01.009. Epub 2017 Jan 18. PMID: 28236982

Dysregulation of KRAS signaling in pancreatic cancer is not associated with KRAS mutations and outcome. Lemstrova R, Brynychova V, Hughes DJ, Hlavac V, Dvorak P, Doherty JE, Murray HA, Crockard M, Oliverius M, Hlavsa J, Honsova E, Mazanec J, Kala Z, Lovecek M, Havlik R, Ehrmann J, Strouhal O, Soucek P, Melichar B, Mohelnikova-Duchonova B. Oncol Lett. 2017 Nov;14(5):5980-5988. doi: 10.3892/ol.2017.6946. Epub 2017 Sep 14. PMID: 29113235

Different clinical presentations of metachronous pulmonary metastases after resection of pancreatic ductal adenocarcinoma: Retrospective study and review of the literature. Lovecek M, Skalicky P, Chudacek J, Szkorupa M, Svebisova H, Lemstrova R, Ehrmann J, Melichar B, Yogeswara T, Klos D, Vrba R, Havlik R, Mohelnikova-Duchonova B. World J Gastroenterol. 2017 Sep 21;23(35):6420-6428. doi: 10.3748/wjg.v23.i35.6420. PMID: 29085191

Age-associated prognostic and predictive biomarkers in patients with breast cancer. Kolečková M, Kolář Z, Ehrmann J, Kořínková G, Trojanec R. Oncol Lett. 2017 Jun;13(6):4201-4207. doi: 10.3892/ol.2017.6000. Epub 2017 Apr 6. PMID: 28599421

Role of regional absorption and gastrointestinal motility on variability in oral absorption of a model drug. Narang AS, Balakrishnan A, Morrison J, Li J, Wang J, Gu H, Taylor K, Santone K, Ehrmann J, Beyer S, Lu X, Ketner R, Pizzano J, Orcutt T, Shields E, Dulac H, Aborn S, Batchelder M, Lentz K. Eur J Pharm Biopharm. 2017 Aug;117:333-345. doi: 10.1016/j.ejpb.2017.04.026. Epub 2017 Apr 25. PMID: 28455207

Transcriptome analysis reveals distinct gene expression profiles in astrocytoma grades II-IV. Narsia N, Ramagiri P, Ehrmann J, Kolar Z. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2017 Sep;161(3):261-271. doi: 10.5507/bp.2017.020. Epub 2017 Apr 26. PMID: 28452381

The fibroblast surface markers FAP, anti-fibroblast, and FSP are expressed by cells of epithelial origin and may be altered during epithelial-to-mesenchymal transition. Kahounová Z, Kurfürstová D, Bouchal J, Kharaishvili G, Navrátil J, Remšík J, Šimečková Š, Študent V, Kozubík A, Souček K. Cytometry A. 2017 Apr 6. doi: 10.1002/cyto.a.23101. [Epub ahead of print] PMID: 28383825

Selective inhibition reveals cyclin-dependent kinase 2 as another kinase that phosphorylates the androgen receptor at serine 81. Jorda R, Bučková Z, Řezníčková E, Bouchal J, Kryštof V. Biochim Biophys Acta. 2017 Nov 17. pii: S0167-4889(17)30310-5. doi: 10.1016/j.bbamcr.2017.11.011. [Epub ahead of print] PMID: 29157894

Cisplatin or LA-12 enhance killing effects of TRAIL in prostate cancer cells through Bid-dependent stimulation of mitochondrial apoptotic pathway but not caspase-10.

Vondálová Blanářová O, Šafaříková B, Herůdková J, Krkoška M, Tománková S, Kahounová Z, Anděra L, Bouchal J, Kharaishvili G, Král M, Sova P, Kozubík A, Hyršlová Vaculová A. PLoS One. 2017 Nov 28;12(11):e0188584. doi: 10.1371/journal.pone.0188584. eCollection 2017. PMID: 29182622

[A case report of peritoneal tuberculosis: the diagnostic role of PET/CT and laparoscopy]. Macháčková H, Pilka R, Losse S, Žurková M, Lošťáková V, Tichý T, Lovečková Y. Ceska Gynekol. 2017 Fall;82(4):300-307. Czech. PMID: 28925274

[30 years of the cochlear implantations in the Czech Republic]. Bouček J, Kluh J, Čada Z, Vokřál J, Černý L, Tichý T, Skřivan J, Betka J, Plzák J. Cas Lek Cesk. 2017 Summer;156(4):178-182. Czech.  PMID: 28862006

Prognostic Influence of Internal Mammary Node Drainage in Patients with Early-stage Breast Cancer. Lukesova L, Vrana D, Svach I, Zlamalova N, Gatek J, Vlachová Z, Matzenauer M, Koranda P, Hruzova K, Tichy T, Melichar B. Anticancer Res. 2016 Dec;36(12):6641-6646. PMID: 27919996

The Role of miR-126 Critical Limb Ischemia Treatment Using Adipose-Derived Stem Cell Therapeutic Factor Concentrate and Extracellular Matrix Microparticles.  Prochazka V, Jurcikova J, Vitkova K, Pavliska L, Porubova L, Lassak O, Buszman P, Fernandes C, Jaluvka F, Spackova I, Lochman I, Prochazka M, Janikova M, Tauber Z, Frankova J,Lachnit M, Hiles M, Johnstone B.: Animal Study (2017) 23, 1-12.

Kapitola v knize:

Tissue examination a diagnostic procedure. Flodrová P., Pika T., Flodr P.: In: Amyloidosis. Ed.: Raquel Wetts.

Androgen Receptor as a Target for Epigenetic Therapy of Castration Resistant Propstate Cancer (CRPC). Smesny Trtkova K.: Recent Advances in Prostate Cancer.2-25.

Publikace 2016

Glycoproteinasporin as a novelplayer in tumourmicroenvironment and cancerprogression. Simkova D, Kharaishvili G, Slabakova E, Murray PG, Bouchal J. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2016 Sep 5. doi: 10.5507/bp.2016.037. PMID: 27605398

Overexpression of filamin-Aprotein is associated with aggressivephenotype and poorsurvivaloutcomes in NSCLCpatientstreated with platinum-basedcombinationchemotherapy. Gachechiladze M, Skarda J, Janikova M, Mgebrishvili G, Kharaishvili G, Kolek V, Grygarkova I, Klein J, Poprachova A, Arabuli M, Kolar Z. Neoplasma. 2016;63(2):274-81.

The dual role of asporin in breast cancer progression. Simkova D, Kharaishvili G, Korinkova G, Ozdian T, Suchánková-Kleplová T, Soukup T, Krupka M, Galandakova A, Dzubak P, Janikova M, Navratil J, Kahounova Z, Soucek K, Bouchal J. Oncotarget 2016 Jul 7. doi: 10.18632/oncotarget.10471.

DNA damage signalling barrier, oxidative stress and treatment-relevant DNA repair factor alterations during progression of human prostate cancer. Kurfurstova D, Bartkova J, Vrtel R, Mickova A, Burdova A, Majera D, Mistrik M, Kral M, Santer FR, Bouchal J, Bartek J. Mol Oncol. 2016 Jun;10(6):879-94. doi: 10.1016/j.molonc.2016.02.005. PMID: 26987799

The AR/NCOA1axisregulatesprostatecancermigration by involvement of PRKD1. Luef B, Handle F, Kharaishvili G, Hager M, Rainer J, Janetschek G, Hruby S, Englberger C, Bouchal J, Santer FR, Culig Z. Endocr Relat Cancer. 2016 Jun;23(6):495-508. doi: 10.1530/ERC-16-0160. PMID: 27255895

Stimulating effect of normal-dosing of fibrates on cell proliferation: word of warning. Cizkova K, Steigerova J, Gursky J, Ehrmann J. Lipids Health Dis. 2016 Sep 22;15(1):164. PMID: 27658584

Protective effect of isoquercitrin against acute dextran sulfate sodium-induced rat colitis depends on the severity of tissue damage. Cibiček N, Roubalová L, Vrba J, Zatloukalová M, Ehrmann J, Zapletalová J, Večeřa R, Křen V, Ulrichová J. Pharmacol Rep. 2016 Sep 19;68(6):1197-1204. doi: 10.1016/j.pharep.2016.07.007. PMID: 27657482

Soluble Epoxide Hydrolase as a Potential Key Factor for Human Prenatal Development. Cizkova K, Rajdova A, Ehrmann J. Cells Tissues Organs. 2016;201(4):277-86. doi: 10.1159/000444674. PMID: 27144772

Long-term survival after resections for pancreatic ductal adenocarcinoma. Single centre study. Lovecek M, Skalicky P, Klos D, Bebarova L, Neoral C, Ehrmann J, Zapletalova J, Svebisova H, Vrba R, Stasek M, Yogeswara T, Havlik R. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2016 Jun;160(2):280-6. doi: 10.5507/bp.2016.011. PMID: 27029600

MiR-205 functions as a tumor suppressor in adenocarcinoma and an oncogene in squamous cell carcinoma of esophagus. Hezova R, Kovarikova A, Srovnal J, Zemanova M, Harustiak T, Ehrmann J, Hajduch M, Sachlova M, Svoboda M, Slaby O. Tumour Biol. 2016 Jun;37(6):8007-18. doi: 10.1007/s13277-015-4656-8. PMID: 26711784

High-grade urothelial bladder cancer in children: A case report and critical analysis of the literature.Kral M, Michalek J, Skarda J, Tichy T, Smakal O, Kodet R, Student V. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2016 Oct 3. doi: 10.5507/bp.2016.045. PMID: 27752150

Importance of Tumour Suppressor Gene Methylation in Sinonasal Carcinomas. Chmelařová M, Sirák I, Mžik M, Sieglová K, Vošmiková H, Dundr P, Němejcová K, Michálek J, Vošmik M, Palička V, Laco J. Folia Biol (Praha). 2016;62(3):110-9. PMID: 27516190

The role of microRNA in metastatic processes of non-small cell lung carcinoma. Pastorkova Z., Škarda J., Andel J.: Biomed Pap Med Fac Univ palácky Olomouc Czech rep (2016) 160 (3) 343-357.

Prognostic significance of miR-23b in combination with P-gp, MRP and LRP/MVP expression in non-small cell lung cancer.Janikova M, Zizkova V, Skarda J, Kharaishvili G, Radova L, Kolar Z. Neoplasma. 2016;63(4):576-87. doi: 10.4149/neo_2016_411. PMID: 27268921

Epigenetic modulation of AR gene expression in prostate cancer DU145 cells with the combination of sodium butyrate and 5'-Aza-2'-deoxycytidine.Fialova B, Luzna P, Gursky J, Langova K, Kolar Z, Trtkova KS. Oncol Rep. 2016 Oct;36(4):2365-74. doi: 10.3892/or.2016.5000. PMID: 27499010

Prospective study of signalling pathways in myeloma bone disease with regard to activity of the disease, extent of skeletal involvement and correlation to bone turnover markers. Minarik J, Hermanova Z, Petrova P, Hrbek J, Zapletalova J, Krhovska P, Flodr P, Pika T, Bacovsky J, Flodrova P, Herman M, Scudla V. Eur J Haematol. 2016 Aug;97(2):201-7. doi: 10.1111/ejh.12708. PMID: 26613192

A Novel Non-Immunoglobulin (non-Ig)/BCL6 Translocation in Diffuse Large B-Cell Lymphoma Involving Chromosome 10q11.21 Loci and Review on Clinical Consequences of BCL6 Rearrangements. Jarosova M, Kriegova E, Schneiderova P, Fillerova R, Prochazka V, Mikesova M, Flodr P, Indrak K, Papajik T. Pathol Oncol Res. 2016 Apr;22(2):233-43. doi: 10.1007/s12253-015-9972-1. Review. PMID: 26319027

Clinicopathological correlations of the immunoprofile in diffuse large B-cell lymphoma NOS - a single institutions experience.Flodr P, Látalová P, Tichý M, Kubová Z, Papajík T, Šváchová M, Radová L, Jarošová M. Cesk Patol. 2016;52(1):47-54. PMID: 27108556

Analytical validity of a microRNA-based assay for diagnosing indeterminate thyroid FNA smears from routinely prepared cytology slides. Benjamin H, Schnitzer-Perlman T, Shtabsky A, Vanden Bussche CJ, Ali SZ, Kolar Z, Pagni F; Rosetta Genomics Group., Bar D, Meiri E. Cancer. 2016 Oct;124(10):711-721. doi: 10.1002/cncy.21731. PMID: 27223344

MMP-19 deficiency causes aggravation of colitis due to defects in innate immune cell function. Brauer R, Tureckova J, Kanchev I, Khoylou M, Skarda J, Prochazka J, Spoutil F, Beck IM, Zbodakova O, Kasparek P, Korinek V, Chalupsky K, Karhu T, Herzig KH, Hajduch M, Gregor M, Sedlacek R. Mucosal Immunol. 2016 Jul;9(4):974-85. doi: 10.1038/mi.2015.117. PMID:26555704

Structure activity relationship studies on cytotoxicity and the effects on steroid receptors of AB-functionalized cholestanes. Rárová L, Steigerová J, Kvasnica M, Bartůněk P, Křížová K, Chodounská H, Kolář Z, Sedlák D, Oklestkova J, Strnad M. J Steroid Biochem Mol Biol. 2016 May;159:154-69. doi: 10.1016/j.jsbmb.2016.03.017. PMID: 26976651

Frequency of chromosome 17 polysomy in relation to CEP17 copy number in a large breast cancer cohort. Koudelakova V, Trojanec R, Vrbkova J, Donevska S, Bouchalova K, Kolar Z, Varanasi L, Hajduch M. Genes Chromosomes Cancer. 2016 May;55(5):409-17. doi: 10.1002/gcc.22337. PMID: 26847577

Long-term follow-up of children and adolescents with primary sclerosing cholangitis and autoimmune sclerosing cholangitis. Smolka V, Karaskova E, Tkachyk O, Aiglova K, Ehrmann J, Michalkova K, Konecny M, Volejnikova J. Hepatobiliary Pancreat Dis Int. 2016 Aug;15(4):412-8. PMID: 27498582

[Multimodal Therapy of Recurrent Malignant Schwannoma]. Kalita O, Cwiertka K, Vrána D, Vaverka M, Tučková L, Megová M. Klin Onkol. 2016 Fall;29(5):364-368. Czech.  PMID: 27739316

Glioblastoma multiforme in patients with history of extracranial cancer: Case series. Kalita O, Trojanec R, Megova M, Hajduch M, Vaverka M, Hrabalek L, Zlevorova M, Drabek J, Tuckova L, Vrbkova J. Clin Neurol Neurosurg. 2016 May;144:39-43. doi: 10.1016/j.clineuro.2016.02.039. PMID: 26971293

Unusual phenotype of pathologically confirmed progressive supranuclear palsy with autonomic dysfunction and cerebellar ataxia.  Mensikova K., Tuckova L., Ehrmann J., Kanovsky P. Medicine (2016) po korektuře

Cranberry intervention in patients with prostate cancer prior to radical  prostatectomy. Clinical, pathological and laboratory findings. Student V., Vidlar A., Bouchal J, Vrbkova J., Kolar Z., Kral M., Kosina P., Vostalova J. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2016; 160:XX.

Familiární amyloidová polyneuropatie – kazuistika / T. Pika, P. Látalová, H. Hůlková, H. Vlášková, P. Otruba, V. Mejzlík, V. Ščudla, Česká a slovenská neurologie a neurochirurgie. 2015, roč. 78, č. 6, s. 710-714.

Publikace 2015

Opposite regulation of MDM2 and MDMX expression in acquisition of mesenchymal phenotype in benign and cancer cells. Slabáková E, Kharaishvili G, Smějová M, Pernicová Z, Suchánková T, Remšík J, Lerch S, Straková N, Bouchal J, Král M, Culig Z, Kozubík A, Souček K. Oncotarget. 2015 Nov 3;6(34):36156-71. doi: 10.18632/oncotarget.5392. PMID: 26416355

BCL2 is an independent predictor of outcome in basal-like triple-negative breast cancers treated with adjuvant anthracycline-based chemotherapy. Bouchalova K, Svoboda M, Kharaishvili G, Vrbkova J, Bouchal J, Trojanec R, Koudelakova V, Radova L, Cwiertka K, Hajduch M, Kolar Z. Tumour Biol. 2015 Jun;36(6):4243-52. doi: 10.1007/s13277-015-3061-7. PMID: 25616695

Histomorphometric diagnostics of renal osteopathy in chronic dialysis patients at high risk of cardiovascular disease. Žamboch K, Krejčí K, Škarda J, Tichý M, Überall I, Skýpalová P, Langová K, Stejskal D, Švesták M, Zahálková J, Ščudla V, Zadražil J. Int Urol Nephrol. 2015 Jul;47(7):1195-201. doi: 10.1007/s11255-015-0989-x. PMID: 25931273

The Changes of Angiogenesis and Immune Cell Infiltration in the Intra- and Peri-Tumoral Melanoma Microenvironment. Židlík V, Brychtová S, Uvírová M, Ziak D, Dvořáčková  J. Int. J. Mol. Sci. 2015 16 (4), 7876-7889. doi: 10.3390/ijms16047876. PMID: 25913374

Cutaneous bacillary angiomatosis due to Bartonella quintana in a renal transplant recipient. Orsag J, Flodr P, Melter O, Tkadlec J, Sternbersky J, Hruby M, Klicova A, Zamboch K, Krejci K, Zadrazil J. Transpl Int. 2015 May;28(5):626-31. doi: 10.1111/tri.12539. PMID: 25652715

Androgenetic alopecia and polymorphism of the androgen receptor gene (SNP rs6152) in patients with benign prostate hyperplasia or prostate cancer. Kucerova R, Bienova M, Kral M, Bouchal J, Trtkova KS, Burdova A, Student V, Kolar Z. J Eur Acad Dermatol Venereol. 2015 Jan;29(1):91-6. doi: 10.1111/jdv.12468. PMID: 24665929

A Novel Non-Immunoglobulin (non-Ig)/BCL6 Translocation in Diffuse Large B-Cell Lymphoma Involving Chromosome 10q11.21 Loci and Review on Clinical Consequences of BCL6 Rearrangements. Jarosova M, Kriegova E, Schneiderova P, Fillerova R, Prochazka V, Mikesova M, Flodr P, Indrak K, Papajik T. Pathol Oncol Res. 2016 Apr;22(2):233-43. doi: 10.1007/s12253-015-9972-1. Review. PMID: 26319027

The Relationship of MiR-21, MiR-126 and MiR-205 to P-Glycoprotein, MRP1 and LRP/MVP in Non-Small Cell Lung Cancer. Žižková V, Škarda J, Janíková M, Lužná P, Radová L, Kurfurstová D, Kolář Z. Austin J. of Cancer and Clinical Research 2015, 2 (5), 1-6.

MMP-19 deficiency causes aggravation of colitis due to defects in innate immune cell function. Brauer R, Tureckova J, Kanchev I, Khoylou M, Skarda J, Prochazka J, Spoutil F, Beck IM, Zbodakova O, Kasparek P, Korinek V, Chalupsky K, Karhu T, Herzig KH, Hajduch M, Gregor M, Sedlacek R. Mucosal Immunol. 2016 Jul;9(4):974-85. doi: 10.1038/mi.2015.117. PMID: 26555704

Loss of PTEN Facilitates Rosiglitazone-Mediated Enhancement of Platinum(IV) Complex LA-12-Induced Apoptosis in Colon Cancer Cells. Lauková J, Kozubík A, Hofmanová J, Nekvindová J, Sova P, Moyer MP, Ehrmann J, Hyršlová Vaculová A. PLoS One. 2015 Oct 22;10(10):e0141020. doi: 10.1371/journal.pone.0141020. PMID: 26492315

Validity of the Morawietz classification for evaluation of periprosthetic tissue. Gallo J, Lužná P, Holinka M, Ehrmann J, Zapletalová J, Lošťák J. Acta Chir Orthop Traumatol Cech. 2015;82(2):126-34. Czech.  PMID: 26317183

 Evaluation of HER2 Gene Status in Breast Cancer Samples with Indeterminate Fluorescence in Situ Hybridization by Quantitative Real-Time PCR. Koudelakova V, Berkovcova J, Trojanec R, Vrbkova J, Radova L, Ehrmann J, Kolar Z, Melichar B, Hajduch M. J Mol Diagn. 2015 Jul;17(4):446-55. doi: 10.1016/j.jmoldx.2015.03.007. PMID: 25956448

Diagnostic and prognostic potential of miR-21, miR-29c, miR-148 and miR-203 in adenocarcinoma and squamous cell carcinoma of esophagus. Hezova R, Kovarikova A, Srovnal J, Zemanova M, Harustiak T, Ehrmann J, Hajduch M, Svoboda M, Sachlova M, Slaby O. Diagn Pathol. 2015 Apr 28;10:42. doi: 10.1186/s13000-015-0280-6. PMID: 25928282

Dynamic changes in microRNA expression profiles reflect progression of Barrett's esophagus to esophageal adenocarcinoma. Slaby O, Srovnal J, Radova L, Gregar J, Juracek J, Luzna P, Svoboda M, Hajduch M, Ehrmann J. Carcinogenesis. 2015 May;36(5):521-7. doi: 10.1093/carcin/bgv023. PMID: 25784377

Low expression of Tlr-1, -2, -4 a il-2, -2r, -10, -10r and TgFb1 in pseudosynovial tissue collected at revision total knee arthroplasty for aseptic loosening. Tománková T, Kriegová E, Fillerová R, Lužná P, Ehrmann J, Gallo J. Acta Chir Orthop Traumatol Cech. 2015;82(1):67-75. Czech.  PMID: 25748664

Spatio-temporal expression of peroxisome proliferator-activated receptor α during human prenatal development. Cizkova K, Rajdova A, Ehrmann J. Basic Clin Pharmacol Toxicol. 2015 Apr;116(4):361-6. doi: 10.1111/bcpt.12326. PMID: 25225039

An adult multifocal medulloblastoma with diffuse acute postoperative cerebellar swelling: immunohistochemical and molecular genetics analysis. Balik V, Trojanec R, Holzerova M, Tuckova L, Sulla I, Megova M, Vaverka M, Hrabalek L, Ehrmann J. Neurosurg Rev. 2015 Jan;38(1):1-10; discussion 10. doi: 10.1007/s10143-014-0556-4. PMID: 24913771

Recurrent salivary pleomorphic adenoma shows increased immunohistologic expression of bcl-2 oncoprotein. Obtulovicova K, Starek I, Salzman R, Kalis A, Ehrmann J, Sicak M, Dvorackova J. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2015 Sep;159(3):460-5. doi: 10.5507/bp.2014.013. Epub 2014 Mar 14. PMID: 24740354

Sarcoidosis of female reproductive organs in a postmenopausal woman: a case report and review of the literature: is there a potential for hormone therapy? Zurkova M, Turkova M, Tichy T, Pilka R, Kolek V, Kriegova E. Menopause. 2015 May;22(5):549-53. doi: 10.1097/GME.0000000000000347. Review. PMID: 25314149

Granular cell basal cell carcinoma: A rare variant. Tichy M, Sen MT. Indian J Dermatol Venereol Leprol. 2015 Jul-Aug;81(4):420-2. doi: 10.4103/0378-6323.158652. No abstract available.  PMID: 26087093

The presence of high-risk human papillomavirus (HPV) E6/E7 mRNA transcripts in a subset of sinonasal carcinomas is evidence of involvement of HPV in its etiopathogenesis. Laco J, Sieglová K, Vošmiková H, Dundr P, Němejcová K, Michálek J, Čelakovský P, Chrobok V, Mottl R, Mottlová A, Tuček L, Slezák R, Chmelařová M, Sirák I, Vošmik M, Ryška A. Virchows Arch. 2015 Oct;467(4):405-15. doi: 10.1007/s00428-015-1812-x. PMID: 26229021

Lupus erythematodes indukovaný léky. Brychtová S, Tichý M. Dermatologie pro praxi 2015, 9(1): 45-46.

Infekce Bartonella benselae jako příčina jednostranné epitrocheátní hnisavé granulomatozní lymfadenitidy. Mihál V., Procházková K., Pospíšilová D., Malý T., Tučková L., Michálková K.: Pediatr. praxi 2015; 16(1): 51–53

 Endobronchiální léčba karcinoidu. Názory a vlastní zkušenosti. Kolek V., Sova M., Fischer O., Jakubec P., Zatloukal J., Losse S., Václavík A., Tichý T, Škarda J., Kolář Z. Studia pneumologica et phthiseologica. 2015, roč. 75, č. 4, s. 154-158

Intradiploická epidermoidní cysta čelní kosti. Mihál V., Krahulík D., Geierová M, Michálková K.

Naše zkušenosti s léčbou pirfineidonem u pacienta s idiopatickou plicní fibrózou, kazuistika. Lošťáková V., Kolek V., Žurková M., Tichý T., Čtvrtlík F, Kriegová E.

Problematika stanovení monoklonálního imunoglobulinu u nemocných s AL. amyloidózou Pika T., Lochman P, Látalová P, Minařík J, Puščiznová P, Bačovský J, Ščudla V.  Klin. Biochem. Metab., 23 (44), 2015, No. 2, p. 37-41

Pagetova kostní choroba?  Skácelová M, Horák P, Dokoupilová E, Kačerová E, Škarda J. Osteologický bulletin. 2015, roč. 20, č. 1, s. 15-20

Familiární amyloidová polyneuropatie – kazuistika Pika T, Látalová P, Hůlková H, Vlášková H, Otruba P, Mejzlík V, Ščudla V. Cesk Slov Neurol N 2015; 78/111(6): 710-714

Folikulární adenom štítné žlázy s cystickou degenerací u čtrnáctileté dívky Mihál V, Venháčová J, Geierová M, Michálková K. Pediatr. praxi 2015; 16(2): 124–126

Sarkoidóza pohybového ústrojí Lošťáková V, Lošťák J, Kriegová E, Žurková M, Tichý T, Hrbek J, Formánek R, Gallo J, Kolek V. Kazuistiky v alergologii, pneumologii a ORL. 2013, roč. 10, Supl.1 (XVIII. Setkání pneumologů a II. Setkání pneumologů a pneumochirurgů, Praha, 6. června 2013), s. 13-14.

High-Grade Non-Invasive Transitional Cell Carcinoma with Osseous Metaplasia of the 3-Year-Old Boy Urinary Bladder Skarda J, Michalek J, Tichy T, Smakal O, Kral M, Kodet R. J Clin Exp Pathol 2015, 5:4

Dlouhodobé výsledky adjuvantní chemoterapie po radikální operaci nemalobuněčného karcinomu plic. Zkušenosti z praxe jednoho centra.  Kolek V, Grygárková I, Kultan J, jakubec P, Szkorupa M, Klein J, Neoral Č, Škarda J, Kolář Z. Stud. Pneumol. Phtiseol 2015, 75 (6), 232-235

Metoda RNAscope pro analýzu exprese HER2 ve vzorcích karcinomů mléčné žlázy s neprokázanou amplifikací. Koleckova M, Korinkova G, Koudelakova V, Patockova J, Sopikova B, Hajduch M, Kolar Z. Onkologie 2015, 9(5), 245-247

 

Publikace 2014

Key tumor suppressor genes inactivated by "greater promoter" methylation and somatic mutations in head and neck cancer. Guerrero-Preston R, Michailidi C, Marchionni L, Pickering CR, Frederick MJ, Myers JN, Yegnasubramanian S, Hadar T, Noordhuis MG, Zizkova V, Fertig E, Agrawal N, Westra W, Koch W, Califano J, Velculescu VE, Sidransky D. Epigenetics. 2014 Jul;9(7):1031-46. doi: 10.4161/epi.29025. PMID: 24786473

The role of high cell density in the promotion of neuroendocrine transdifferentiation of prostate cancer cells. Pernicová Z, Slabáková E, Fedr R, Šimečková Š, Jaroš J, Suchánková T, Bouchal J, Kharaishvili G, Král M, Kozubík A, Souček K. Mol Cancer. 2014 May 20;13:113. doi: 10.1186/1476-4598-13-113. PMID: 24884804

Platinum(IV) complex LA-12 exerts higher ability than cisplatin to enhance TRAIL-induced cancer cell apoptosis via stimulation of mitochondrial pathway. Jelínková I, Šafaříková B, Vondálová Blanářová O, Skender B, Hofmanová J, Sova P, Moyer MP, Kozubík A, Kolář Z, Ehrmann J, Hyršlová Vaculová A. Biochem Pharmacol. 2014 Dec 1;92(3):415-24. doi: 10.1016/j.bcp.2014.09.013. PMID: 25285768

Relation of ETS transcription factor family member ERG, androgen receptor and topoisomerase 2β expression to TMPRSS2-ERG fusion status in prostate cancer. Kolar Z, Burdova A, Jamaspishvili T, Bouchal J, Kucerova R, Bienova M, Kral M, Student V. Neoplasma. 2014;61(1):9-16. PMID: 24195515

TMPRSS2-ERG gene fusion in prostate cancer. Burdova A, Bouchal J, Tavandzis S, Kolar Z. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2014 Dec;158(4):502-10. doi: 10.5507/bp.2014.065. Review. PMID: 25485532

Androgenetic alopecia and polymorphism of the androgen receptor gene (SNP rs6152) in patients with benign prostate hyperplasia or prostate cancer. Kucerova R, Bienova M, Kral M, Bouchal J, Trtkova KS, Burdova A, Student V, Kolar Z. J Eur Acad Dermatol Venereol. 2015 Jan;29(1):91-6. doi: 10.1111/jdv.12468. PMID: 24665929

Spatio-temporal expression of peroxisome proliferator-activated receptor α during human prenatal development. Cizkova K, Rajdova A, Ehrmann J. Basic Clin Pharmacol Toxicol. 2015 Apr;116(4):361-6. doi: 10.1111/bcpt.12326. PMID: 25225039

Diffuse large B-cell lymphoma: the history, current view and new perspectives.Flodr P, Latalova P, Tichy M, Kubova Z, Papajik T, Svachova M, Vrzalikova K, Radova L, Jarosova M, Murray P. Neoplasma. 2014;61(5):491-504. doi: 10.4149/neo_2014_062. Review. PMID: 25030433

Primitive neuroectodermal tumor (PNET) of the lung in an adult woman. Gachechiladze M, Skarda J, Ibrahim M, Tichý T, Flodr P, Latálová P, Ehrmann J, Trojanec R, Kolář Z. World J Surg Oncol. 2014 Dec 5;12:374. doi: 10.1186/1477-7819-12-374. PMID: 25475214

[Use of archival formalin-fixed, paraffin-embedded (FFPE) tissue samples for molecular genetic analysis in diffuse large B-cell lymphoma (DLBCL)]. Jarošová M, Kučerová J, Flodr P, Mikešová M, Procházka V, Papajík T. Cesk Patol. 2014 Apr;50(2):95-9. Czech.  PMID: 24758506

Unusual recurrent rectal carcinoma: a cancer field theory viewpoint. Vyslouzil K, Brychtova S, Zboril P, Skalicky P, Vomackova K, Bezdekova M, Brychta T. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2014 Sep;158(3):433-7. doi: 10.5507/bp.2012.091. PMID: 23128827

Epstein-Barr virus, the germinal centre and the development of Hodgkin's lymphoma. Mohamed G, Vrzalikova K, Cader FZ, Vockerodt M, Nagy E, Flodr P, Yap LF, Diepstra A, Kluin PM, Rosati S, Murray P. J Gen Virol. 2014 Sep;95(Pt 9):1861-9. doi: 10.1099/vir.0.066712-0. PMID: 24893782

Predictive parameters for internal mammary node drainage in patients with early breast cancer. Lukesova L, Vrana D, Gatek J, Koranda P, Cwiertka K, Radova L, Melichar B, Prouzova Z, Sramek V, Svach I. Tumori. 2014 May-Jun;100(3):254-8. doi: 10.1700/1578.17194. PMID: 25076234

Soluble interleukin-2 receptor level predicts survival in patients with follicular lymphoma treated with cyclophosphamide, doxorubicin, vincristine and prednisone chemotherapy in the rituximab era. Procházka V, Papajík T, Faber E, Raida L, Kapitáňová Z, Langová K, Prouzová Z, Jarošová M, Indrák K. Leuk Lymphoma. 2014 Jul;55(7):1584-90. doi: 10.3109/10428194.2013.850167. PMID: 24180329

An adult multifocal medulloblastoma with diffuse acute postoperative cerebellar swelling: immunohistochemical and molecular genetics analysis. Balik V, Trojanec R, Holzerova M, Tuckova L, Sulla I, Megova M, Vaverka M, Hrabalek L, Ehrmann J. Neurosurg Rev. 2015 Jan;38(1):1-10; discussion 10. doi: 10.1007/s10143-014-0556-4. PMID: 24913771

Comparison of periprosthetic tissues in knee and hip joints: differential expression of CCL3 and DC-STAMP in total knee and hip arthroplasty and similar cytokine profiles in primary knee and hip osteoarthritis. Tomankova T, Kriegova E, Fillerova R, Luzna P, Ehrmann J, Gallo J. Osteoarthritis Cartilage. 2014 Nov;22(11):1851-60. doi: 10.1016/j.joca.2014.08.004. PMID: 25151085

Direct detection of the AR-E211 G > A gene polymorphism from blood and tissue samples without DNA isolation. Reptova S, Trtkova KS, Kolar Z. Pathol Oncol Res. 2014 Apr;20(2):223-7. doi: 10.1007/s12253-013-9671-8. PMID: 24634161

Time-dependent expression of cytochrome p450 epoxygenases during human prenatal development. Cizkova K, Konieczna A, Erdosova B, Ehrmann J. Organogenesis. 2014 Jan 1;10(1):53-61. doi: 10.4161/org.27911. PMID: 24492490

Triple negative breast cancer - BCL2 in prognosis and prediction. Review. Bouchalova K, Kharaishvili G, Bouchal J, Vrbkova J, Megova M, Hlobilkova A. Curr Drug Targets. 2014;15(12):1166-75. Review. PMID: 25374001

The role of cancer-associated fibroblasts, solid stress and other microenvironmental factors in tumor progression and therapy resistance. Kharaishvili G, Simkova D, Bouchalova K, Gachechiladze M, Narsia N, Bouchal J. Cancer Cell Int. 2014 May 16;14:41. doi: 10.1186/1475-2867-14-41. Review: PMID: 24883045

Detection of minimal residual disease in lung cancer. Chudacek J, Bohanes T, Klein J, Benedikova A, Srovnal J, Szkorupa M, Skalicky P, Skarda J, Hajduch M, Neoral C. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2014 Jun;158(2):189-93. doi: 10.5507/bp.2013.019. Review. PMID: 23558472

Vztah rizikových faktorů mezi metabolickým syndromem a nealkoholickým ztučněním jater u dětí a dospívajících Smolka V, Ehrmann J jr, Tkachyk O, Zápalka M. Časopis lékařů českých (2014) 153, 2, 91-97.

AL amyloidóza v obrazech Látalová P, Pika T, Flodr P. Transfuze Hematol dnes (2014) 20, 76-80.

Stevensův-Johnsonův syndrom při infekci dýchacích cest způsobené Mycoplasma pneumoniae Šigutová L, Klásková E, Rohanová M, Špenerová M, Saitz J, Kopřiva F, Brychtová S, Smolka V. Pediatrie praxi (2014) 15)5,

Aktinická keratóza Bienová M, Kučerová R. Brychtová S. Dermatovenerologie (2014) 5, 6-10.

CD30 antigen v histopatologické diagnostice (stručná charakteristika) Prouzová Z, Soukup J, Procházka V.

Histopatologická  diagnostika nádorů centrálního nervového systému Hermanová M, Kolář Z.

Amyloidóza a postižení srdce Pika T, Vymětal J, Látalová P. Kardioonkologie  Grada Publishing ISBN 978-80-247-4838-2

Diagnostika a stratifikace systémové AL amyloidóza ve světle „Doporučení České myelomové skupiny 2013“ Ščudla V, Pika T, Látalová P, Flodr P, Maixner V, Hájek R. Klin Biochem Metab (2014) 22 (43) 2, 49-60.

Klinická problematika IgM monoklonálních gamapatií Pika T, Flodr P, Novák M, Lochman P, Látalová P, Minařík J, Ščudla V. Klin Biochem Metab (2014) 22 (43) 2, 61-64.

Publikace 2013

Markedly asymmetric presentation in multiple system atrophy. Batla A, Stamelou M, Mensikova K, Kaiserova M, Tuckova L, Kanovsky P, Quinn N, Bhatia KP. Parkinsonism Relat Disord. 2013 Oct;19(10):901-5. doi: 10.1016/j.parkreldis.2013.05.004. PMID: 23746453

Mitochondrial changes in adenocarcinoma of the pancreas. Novotný R, Ehrmann J, Tozzi di Angelo I, Procházka V, Klos D, Loveček M, Kysučan J, Havlík R. Ultrastruct Pathol. 2013 May;37(3):227-31. doi: 10.3109/01913123.2013.788306. PMID: 23650995

Suppression of the LMP2A target gene, EGR-1, protects Hodgkin's lymphoma cells from entry to the EBV lytic cycle. Vockerodt M, Wei W, Nagy E, Prouzova Z, Schrader A, Kube D, Rowe M, Woodman CB, Murray PG. J Pathol. 2013 Aug;230(4):399-409. doi: 10.1002/path.4198. PMID: 23592216

Progressive supranuclear palsy phenotype mimicking synucleinopathies. Menšíková K, Matěj R, Tučková L, Rusina R, Ehrmann J, Kaňovský P. J Neurol Sci. 2013 Jun 15;329(1-2):34-7. doi: 10.1016/j.jns.2013.03.008. PMID: 23590894

Down-regulation of BLIMP1α by the EBV oncogene, LMP-1, disrupts the plasma cell differentiation program and prevents viral replication in B cells: implications for the pathogenesis of EBV-associated B-cell lymphomas. Vrzalikova K, Vockerodt M, Leonard S, Bell A, Wei W, Schrader A, Wright KL, Kube D, Rowe M, Woodman CB, Murray PG. Blood. 2011 Jun 2;117(22):5907-17. doi: 10.1182/blood-2010-09-307710. PMID: 21411757

Effect of histone deacetylase and DNA methyltransferase inhibitors on the expression of the androgen receptor gene in androgen-independent prostate cancer cell lines. Fialova B, Smesny Trtkova K, Paskova L, Langova K, Kolar Z. Oncol Rep. 2013 May;29(5):2039-45. doi: 10.3892/or.2013.2344. PMID: 23503510

Different effect of sodium butyrate on cancer and normal prostate cells. Paskova L, Smesny Trtkova K, Fialova B, Benedikova A, Langova K, Kolar Z. Toxicol In Vitro. 2013 Aug;27(5):1489-95. doi: 10.1016/j.tiv.2013.03.002. PMID: 23524101

PROCHÁZKA, V., JAROŠOVÁ, M., PROUZOVÁ, Z., GEIEROVÁ, M., PAPAJÍK, T., INDRÁK, K.: Klinické a biologické prognostické faktory u maligních lymfomů. Transfuze a hematologie dnes 2013, 19, 76-87.

PROUZOVÁ, Z., BRYCHTOVÁ, S.:Paraneoplastický neurologický syndrom u 64letého pacienta s malobuněčným karcinomem plic. Klinická onkologie 2012, 25 (6) 471-475.

Publikace 2012

Merkel cell carcinoma. Case report. Pink R, Molitor M, Ehrmann J, Tvrdy P, Michl P, Pazdera J. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2012;158(1):158-60. doi: 10.5507/bp.2012.034. PMID: 23073525

Merkel cell carcinoma. A review. Pink R, Ehrmann J, Molitor M, Tvrdy P, Michl P, Pazdera J, Hanuliak J. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2012 Sep;156(3):213-7. doi: 10.5507/bp.2012.033. Review. PMID: 23069886

Peroxisome proliferator-activated receptors in regulation of cytochromes P450: new way to overcome multidrug resistance? Cizkova K, Konieczna A, Erdosova B, Lichnovska R, Ehrmann J. J Biomed Biotechnol. 2012;2012:656428. doi: 10.1155/2012/656428. Review. PMID: 23193364

Hepatoprotective effect of MMP-19 deficiency in a mouse model of chronic liver fibrosis. Jirouskova M, Zbodakova O, Gregor M, Chalupsky K, Sarnova L, Hajduch M, Ehrmann J, Jirkovska M, Sedlacek R. PLoS One. 2012;7(10):e46271. doi: 10.1371/journal.pone.0046271. PMID: 23056273

Analysis of the prognostic impact of nestin expression in non-small cell lung cancer. Skarda J, Kolar Z, Janikova M, Radova L, Kolek V, Fridman E, Kopolovic J. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2012 Jun;156(2):135-42. doi: 10.5507/bp.2012.036. PMID: 22837134

Differentiation pathways in carcinogenesis and in chemo- and radioresistance. Janikova M, Skarda J. Neoplasma. 2012;59(1):6-17. doi: 10.4149/neo_2012_002. Review. PMID: 22017591

Analysis of Snail-1, E-cadherin and claudin-1 expression in colorectal adenomas and carcinomas. Bezdekova M, Brychtova S, Sedlakova E, Langova K, Brychta T, Belej K. Int J Mol Sci. 2012;13(2):1632-43. doi: 10.3390/ijms13021632. PMID: 22408413

Evaluation of candidate biomarkers to predict cancer cell sensitivity or resistance to PARP-1 inhibitor treatment. Oplustilova L, Wolanin K, Mistrik M, Korinkova G, Simkova D, Bouchal J, Lenobel R, Bartkova J, Lau A, O'Connor MJ, Lukas J, Bartek J. Cell Cycle. 2012 Oct 15;11(20):3837-50. doi: 10.4161/cc.22026. PMID: 22983061

Mechanisms of natural brassinosteroid-induced apoptosis of prostate cancer cells. Steigerová J, Rárová L, Oklešt'ková J, Křížová K, Levková M, Sváchová M, Kolář Z, Strnad M. Food Chem Toxicol. 2012 Nov;50(11):4068-76. doi: 10.1016/j.fct.2012.08.031. PMID: 22939933

Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth. Hamerlik P, Lathia JD, Rasmussen R, Wu Q, Bartkova J, Lee M, Moudry P, Bartek J Jr, Fischer W, Lukas J, Rich JN, Bartek J. J Exp Med. 2012 Mar 12;209(3):507-20. doi: 10.1084/jem.20111424. PMID: 22393126

A comparison of Direct sequencing, Pyrosequencing, High resolution melting analysis, TheraScreen DxS, and the K-ras StripAssay for detecting KRAS mutations in non small cell lung carcinomas. Jancik S, Drabek J, Berkovcova J, Xu YZ, Stankova M, Klein J, Kolek V, Skarda J, Tichy T, Grygarkova I, Radzioch D, Hajduch M. J Exp Clin Cancer Res. 2012 Sep 20;31:79. doi: 10.1186/1756-9966-31-79. PMID: 22995035

The role of BRCA1 in non-small cell lung cancer. Gachechiladze M, Skarda J. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2012 Sep;156(3):200-3. doi: 10.5507/bp.2012.049. Review. PMID: 23069884

BLIMP1α, the master regulator of plasma cell differentiation is a tumor supressor gene in B cell lymphomas. Vrzalikova K, Woodman CB, Murray PG. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2012 Mar;156(1):1-6. doi: 10.5507/bp.2012.003. Review. PMID: 22580854

ÜBERALL, I., GREGAR, J.: Molekulární patologie nádorů. In: Černoch et al. (ed) Prekancerózy v trávicím traktu. Grada

HOFMANNOVÁ, L., STEIGEROVÁ, J., STRNAD, M.: Anticancer Activities of Brassinosteroids. In: Perreira-Netto (ed) Brassinosteroids Practical Applications in Agriculture and Human Health (2012) 84-93.

Publikace 2011

Analysis of CD40 expression in breast cancer and its relation to clinicopathological characteristics. Slobodova Z, Ehrmann J, Krejci V, Zapletalova J, Melichar B. Neoplasma. 2011;58(3):189-97. PMID: 21391734

Quadriplex model enhances urine-based detection of prostate cancer. Jamaspishvili T, Kral M, Khomeriki I, Vyhnankova V, Mgebrishvili G, Student V, Kolar Z, Bouchal J. Prostate Cancer Prostatic Dis. 2011 Dec;14(4):354-60. doi: 10.1038/pcan.2011.32. PMID: 21788966

Transcriptional coactivators p300 and CBP stimulate estrogen receptor-beta signaling and regulate cellular events in prostate cancer. Bouchal J, Santer FR, Höschele PP, Tomastikova E, Neuwirt H, Culig Z. Prostate. 2011 Mar 1;71(4):431-7. doi: 10.1002/pros.21257. PMID: 20859991

Cetuximab enhances the anti-proliferative effect of trastuzumab in ERBB2 over-expressing breast cancer cells--preliminary study. Uberall I, Krízová K, Steigerová J. Klin Onkol. 2011;24(5):356-60. PMID: 22070017

Immunohistochemical localization and analysis of kallikrein-related peptidase 7 and 11 expression in paired cancer and benign foci in prostate cancer patients. Jamaspishvili T, Scorilas A, Kral M, Khomeriki I, Kurfurstova D, Kolar Z, Bouchal J. Neoplasma. 2011;58(4):298-303. PMID: 21520985

Wnt signaling in prostate development and carcinogenesis. Kharaishvili G, Simkova D, Makharoblidze E, Trtkova K, Kolar Z, Bouchal J. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2011 Mar;155(1):11-8. Review. PMID: 21475372

Inhibition of the acetyltransferases p300 and CBP reveals a targetable function for p300 in the survival and invasion pathways of prostate cancer cell lines. Santer FR, Höschele PP, Oh SJ, Erb HH, Bouchal J, Cavarretta IT, Parson W, Meyers DJ, Cole PA, Culig Z. Mol Cancer Ther. 2011 Sep;10(9):1644-55. doi: 10.1158/1535-7163.MCT-11-0182. PMID: 21709130

Androgen depletion induces senescence in prostate cancer cells through down-regulation of Skp2. Pernicová Z, Slabáková E, Kharaishvili G, Bouchal J, Král M, Kunická Z, Machala M, Kozubík A, Souček K. Neoplasia. 2011 Jun;13(6):526-36. PMID: 21677876

Phosphaturic mesenchymal tumour of the sinonasal area: case report and review of the literature. Komínek P, Stárek I, Geierová M, Matoušek P, Zeleník K. Head Neck Oncol. 2011 Mar 16;3:16. doi: 10.1186/1758-3284-3-16. Review. PMID: 21410940

Genetic determinants of prostate cancer: a review. Kral M, Rosinska V, Student V, Grepl M, Hrabec M, Bouchal J. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2011 Mar;155(1):3-9. Review. PMID: 21475371

Differential expression of ABC transporters (MDR1, MRP1, BCRP) in developing human embryos. Konieczna A, Erdösová B, Lichnovská R, Jandl M, Cížková K, Ehrmann J. J Mol Histol. 2011 Dec;42(6):567-74. doi: 10.1007/s10735-011-9363-1. PMID: 22012127

Changes of microRNAs-192, 196a and 203 correlate with Barrett's esophagus diagnosis and its progression compared to normal healthy individuals. Luzna P, Gregar J, Uberall I, Radova L, Prochazka V, Ehrmann J Jr. Diagn Pathol. 2011 Nov 17;6:114. doi: 10.1186/1746-1596-6-114. PMID: 22094011

Pink R., Ehrmann J., Molitor P., Tvrdý P., Michl P, Pazdera J.: Karcinom z Merkelových buněk. Čs. Stomatologie. Praktické zubní lékařství (2011) 111, 129-130.

Krump M., Ehrmann J.: Prekancerózné léze – klinicky a histopatologicky. Praktické zubní lékařství (2011) 111, 130-131.

Publikace 2010

Telomere attrition occurs during ex vivo expansion of human dental pulp stem cells. Mokry J, Soukup T, Micuda S, Karbanova J, Visek B, Brcakova E, Suchanek J, Bouchal J, Vokurkova D, Ivancakova R. J Biomed Biotechnol. 2010;2010:673513. doi: 10.1155/2010/673513. PMID: 20976265

Transcriptional coactivators p300 and CBP stimulate estrogen receptor-beta signaling and regulate cellular events in prostate cancer. Bouchal J, Santer FR, Höschele PP, Tomastikova E, Neuwirt H, Culig Z. Prostate. 2011 Mar 1;71(4):431-7. doi: 10.1002/pros.21257. PMID: 20859991

Urine markers in monitoring for prostate cancer. Jamaspishvili T, Kral M, Khomeriki I, Student V, Kolar Z, Bouchal J. Prostate Cancer Prostatic Dis. 2010 Mar;13(1):12-9. doi: 10.1038/pcan.2009.31. Review. PMID: 19652665

Replication stress and oxidative damage contribute to aberrant constitutive activation of DNA damage signalling in human gliomas. Bartkova J, Hamerlik P, Stockhausen MT, Ehrmann J, Hlobilkova A, Laursen H, Kalita O, Kolar Z, Poulsen HS, Broholm H, Lukas J, Bartek J. Oncogene. 2010 Sep 9;29(36):5095-102. doi: 10.1038/onc.2010.249. PMID: 20581868

Identification of CD133+/nestin+ putative cancer stem cells in non-small cell lung cancer. Janikova M, Skarda J, Dziechciarkova M, Radova L, Chmelova J, Krejci V, Sedlakova E, Zapletalova J, Langova K, Klein J, Grygarkova I, Kolek V. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2010 Dec;154(4):321-6. PMID: 21293543

Moyamoya disease is associated with endothelial activity detected by anti-nestin antibody. Chmelova J, Kolar Z, Prochazka V, Curik R, Dvorackova J, Sirucek P, Kraft O, Hrbac T. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2010 Jun;154(2):159-62. PMID: 20668498

Brassinosteroids cause cell cycle arrest and apoptosis of human breast cancer cells. Steigerová J, Oklešťková J, Levková M, Rárová L, Kolář Z, Strnad M. Chem Biol Interact. 2010 Dec 5;188(3):487-96. doi: 10.1016/j.cbi.2010.09.006. PMID: 20833159

Binding of AR to SMRT/N-CoR complex and its co-operation with PSA promoter in prostate cancer cells treated with natural histone deacetylase inhibitor NaB. Trtkova K, Paskova L, Matijescukova N, Strnad M, Kolar Z. Neoplasma. 2010;57(5):406-14. PMID: 20568894

The immunohistochemical expression of BNIP3 protein in non-small-cell lung cancer: a tissue microarray study. Uberall I, Kolek V, Klein J, Krejcí V, Stastná J, Radová L, Skarda J, Fridman E. APMIS. 2010 Aug;118(8):565-70. doi: 10.1111/j.1600-0463.2010.02616.x. PMID: 20666737

Genetické riziko karcinomu prostaty.  KRÁL, M. - VYHNÁLKOVÁ V. - ŠTUDENT V. - BOUCHAL J.
Čes. Urologie (2010) 14(3), 139-147.

Fibroblasty-buňky známé či neznámé.  BRYCHTOVÁ, S. - BEZDĚKOVÁ M. - BRYCHTA T.
Česko-slovenská patologie (2010) 46, 29-32.

Cyclin-dependent kinases inhibitor bohemine exhibits no embryotoxic effects. KOLÁŘ, Z. - EHRMANN J. - KNILLOVÁ J. - STRNAD M. Recent Advances in Clinical Medicine. 2010

Autofagie ve vztahu k nemocem.  ÜBERALL, I. Vesmír (2010) 88, 41-44.

Analýza abiogeneze v kostní dřeni u plazmocytárního myelomu.  TICHÝ, M. - TICHÁ V. - ŠČUDLA V. - ŠVÁCHOVÁ M. - ZAPLETALOVÁ J. Česko-slovenská patologie (2010) 46, 15-19

Publikace 2009

The Role of PPARs in MDR - a lesson from embryonic development. Konieczna A, Lichnovka R, Erdosova B, Ehrmann J. Neoplasma. 2009;56(4):279-83. Review. PMID: 19469651

Dumbbell-shaped peripheral primitive neuroectodermal tumor of the spine--case report and review of the literature. Hrabálek L, Kalita O, Svebisova H, Ehrmann J Jr, Hajduch M, Trojanec R, Kala M. J Neurooncol. 2009 Apr;92(2):211-7. doi: 10.1007/s11060-008-9744-9. Review. PMID: 19050994

CD151 regulates tumorigenesis by modulating the communication between tumor cells and endothelium. Sadej R, Romanska H, Baldwin G, Gkirtzimanaki K, Novitskaya V, Filer AD, Krcova Z, Kusinska R, Ehrmann J, Buckley CD, Kordek R, Potemski P, Eliopoulos AG, Lalani el-N, Berditchevski F. Mol Cancer Res. 2009 Jun;7(6):787-98. doi: 10.1158/1541-7786.MCR-08-0574. PMID:19531562

Acute aortic dissection complicated by fistula from aorta to right ventricle through ventricular septum. Marek D, Nemec P, Maderová K, Herman M, Gwozdzievicz M, Troubil M, Flodr P, Lukl J. Cardiovasc Pathol. 2009 Sep-Oct;18(5):301-7. doi: 10.1016/j.carpath.2008.08.002. PMID: 19144552

Analysis of VEGF, Flt-1, Flk-1, nestin and MMP-9 in relation to astrocytoma pathogenesis and progression. Hlobilkova A, Ehrmann J, Knizetova P, Krejci V, Kalita O, Kolar Z. Neoplasma. 2009;56(4):284-90. PMID: 1947305

[Turner syndrome is associated with increased cardiovascular morbidity and mortality]. Berková M, Berka Z, Krcová Z. Vnitr Lek. 2009 May;55(5):523-8. Czech.  PMID: 19514620

[Turner's syndrome requires multidisciplinary approach]. Berková M, Berka Z, Krcová Z. Vnitr Lek. 2009 May;55(5):501-5. Review. Czech.  PMID: 19514616

RNA editing in humancancer: review.

Skarda J, Amariglio N, Rechavi G.

APMIS. 2009 Aug;117(8):551-7. Retraction in: APMIS. 2010 Apr;118(4):337.

The expression of three genes in primary non-small cell lung cancer is associated with metastatic spread to the brain. Grinberg-Rashi H, Ofek E, Perelman M, Skarda J, Yaron P, Hajdúch M, Jacob-Hirsch J, Amariglio N, Krupsky M, Simansky DA, Ram Z, Pfeffer R, Galernter I, Steinberg DM, Ben-Dov I, Rechavi G, Izraeli S. Clin Cancer Res. 2009 Mar 1;15(5):1755-61. doi: 10.1158/1078-0432.CCR-08-2124. PMID: 19190132

Alopecia:  In Encyclopedia of Molecular Mechanisms of Disease Lang BEZDEKOVA, M. - BRYCHTOVA S. - KOLAR Z. - BRYCHTA T. - KUCEROVA R. - BIENOVA M.
Florian (Ed.): ISBN: 978-3-540-67136-7

Expression of Intermediate Filament Nestin in Bloood Vessels of Neural and Non Neural Tissues.  MOKRÝ, J. - EHRMANN J. - KARBANOVÁ J. - ČÍŽKOVÁ D. - SOUKUP T. - SUCHÁNEK J. - FILIP S. - KOLÁŘ Z. Acta Medica (Hradec Králové) (2009), 51, 173-179.

Publikace 2008

The role of vascular endothelial growth factors and their receptors in malignant melanomas. Brychtova S, Bezdekova M, Brychta T, Tichy M. Neoplasma. 2008;55(4):273-9. PMID: 18505336

The stem cell marker CD133 (Prominin-1) is expressed in various human glandular epithelia. Karbanová J, Missol-Kolka E, Fonseca AV, Lorra C, Janich P, Hollerová H, Jászai J, Ehrmann J, Kolár Z, Liebers C, Arl S, Subrtová D, Freund D, Mokry J, Huttner WB, Corbeil D. J Histochem Cytochem. 2008 Nov;56(11):977-93. doi: 10.1369/jhc.2008.951897. PMID: 18645205

Re-expression of nestin in the myocardium of postinfarcted patients. Mokry J, Pudil R, Ehrmann J, Cizkova D, Osterreicher J, Filip S, Kolar Z. Virchows Arch. 2008 Jul;453(1):33-41. doi: 10.1007/s00428-008-0631-8. PMID: 18546018

Kam kráčíte glitazony?  BRYCHTA, T. - BRYCHTOVÁ S. Remedia 2008; 4, 287-92

Farmakoterapie obezity.  BRYCHTA, T. - BRYCHTOVÁ S. Interní medicína pro praxi 2008; 10, 44-7

Lékové postižení jater – současný stav problematiky se zaměřením na morfologický obraz. EHRMANN, J. - STROJIL J. Česko-slovenská patologie a soudní lékařství 2008; 1, 4-7

Thiazolidindiony, PPAR receptory a metabolický syndrom.

BRYCHTA, T. - BEN YAHIA - R. - BRYCHTOVÁ S. - LICHNOVSKÁ - STEJSKAL P.
Mediforum 2008.

Potential Prognostic and Predictive Factors in Diffuse Large B-cell Lymphoma – the role of NFkappaB. FLODR, P. - TICHÝ M. - KUBOVÁ Z. - PAPAJÍK T. - KREJČÍ V. - FRIEDMAN E.
EJC supplements 2008; 6(9): 113-114

Histopatologický atlas, ISBN 978-80-247-1650-3 Grada. BRYCHTOVÁ, S. - HLOBILKOVÁ A.

Nastavení cookies a ochrany soukromí

Na našich webových stránkách používáme soubory cookies a případné další síťové identifikátory, které mohou obsahovat osobní údaje (např. jak procházíte naše stránky). My a někteří poskytovatelé námi využívaných služeb, máme k těmto údajům ve Vašem zařízení přístup nebo je ukládáme. Tyto údaje nám pomáhají provozovat a zlepšovat naše služby. Pro některé účely zpracování takto získaných údajů je vyžadován Váš souhlas. Svůj souhlas můžete kdykoliv změnit nebo odvolat (odkaz najdete v patě stránek).

(Technické cookies nezbytné pro fungování stránek. Neobsahují žádné identifikační údaje.)
(Slouží ke statistickým účelům - měření a analýze návštěvnosti. Sbírají pouze anonymní data.)
(Jsou určeny pro propagační účely, měření úspěšnosti propagačních kampaní apod.)